NGS Automation Engineer

Predicine, Inc.; Hayward (CA); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Medical Coverage

Dental Coverage

Vision Coverage

401(k) Matching

Stock Allocation

Sabbatical after 5 years

Daily lunch provided

Job summary

Predicine, Inc. is seeking an NGS Automation Engineer (Laboratory) in Hayward, CA, to design, optimize, and support automated workflows in our sequencing pipeline.

The role focuses on integrating liquid handling systems with NGS assays and collaborating with lab operations and IT to improve efficiency and accuracy. The ideal candidate has 1–3+ years in lab automation or NGS, hands-on experience with Hamilton systems and Venus software, and a strong eye for process development and regulatory

Qualifications

• Bachelor's degree in Engineering, Biotechnology, Biology, or related field.
• 1–3+ years in laboratory automation or NGS-related roles.
• Familiarity with Hamilton liquid handling systems and Venus software.
• Exposure to lab automation platforms and instruments (Agilent, Bio-Rad, Thermo Fisher).
• Understanding of barcoding and sample traceability.
• Strong problem-solving and documentation skills.
• Knowledge of CLIA/CAP regulatory concepts is a plus.

Responsibilities

• Design and support automated liquid handling for NGS assays.
• Translate manual processes to automated workflows.
• Create and maintain SOPs and quality documentation.
• Assist with IQ/OQ/PQ and change control.
• Collaborate with IT, Facilities, Lab Ops across teams.

Skills

NGS Experience

Automation

Cross-functional

Education

Bachelor's degree in Engineering

Biology/Biotechnology background

Tools

Hamilton

Venus

BIOlims

Agilent

Thermo Fisher

Job description

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NGS Automation Engineer

Full Time Professional IVD/Automation, Hayward, CA, US

23 days ago Requisition ID: 1095

Job Title: Automation Engineer (Laboratory) – NGS / Liquid Biopsy

Predicine is a Silicon Valley-based global precision medicine company committed to developing first- and best-in-class liquid biopsy cancer diagnostics. Our innovative cell-free DNA and cell-free RNA liquid biopsy technology empowers biopharma partners in clinical drug development and oncology research. We provide molecular insights to top 10 MNC BioPharma companies supporting biomarker-driven clinical trials across the US, EU, and APAC (including China). We believe our people are our greatest asset and are dedicated to a thriving, inclusive workplace built on Integrity, Innovation, Quality, Respect, Courage, Collaboration, Caring, and Communication.

About the Role

We are seeking a motivated Automation Engineer with a strong interest or hands-on experience in Next-Generation Sequencing (NGS), laboratory automation, and liquid handling systems to join our growing team. You'll help design, optimize, and support automated workflows that improve the efficiency, scalability, and precision of our sequencing pipeline — working cross-functionally with lab operations, IT, and quality teams. This is a great opportunity for an engineer looking to grow their career in molecular diagnostics, precision medicine, and cutting-edge automation technology.

Key Responsibilities

• Design, develop, and support automated liquid handling systems for NGS assays
• Assist in translating and optimizing manual laboratory processes onto automated platforms
• Provide training and technical support during rollout of new automated methods
• Author and maintain SOPs (Standard Operating Procedures) and quality documentation for regulatory compliance
• Support instrument configuration documentation (IQ/OQ/PQ) and change control
• Complete quality documentation and ensure adherence to internal and regulatory standards
• Collaborate with cross-functional teams including IT, Facilities, and Lab Operations

Qualifications

• Bachelor's degree in Engineering, Biotechnology, Biology, or a related field
• 1–3+ years of laboratory automation, biotech, or NGS-related experience (recent graduates with strong internship/research automation experience welcome to apply)
• Experience or familiarity with Hamilton liquid handling systems and Venus software preferred; scheduling software experience a plus
• Exposure to lab automation platforms and instrumentation (e.g., Agilent, Bio-Rad, Thermo Fisher) and lab software (e.g., BIOlims) preferred
• Understanding of barcoding, labware management, and sample traceability tools
• Interest in process development, scale-up, and troubleshooting within a lab or manufacturing setting
• Strong problem-solving skills and attention to detail
• Excellent written and verbal communication skills, with ability to document technical processes clearly
• Familiarity with regulatory compliance and configuration management concepts (CLIA/CAP a plus)

Why Join Predicine

• Work at the forefront of precision medicine, oncology diagnostics, and liquid biopsy technology
• Competitive salary and comprehensive benefits, including medical, dental, and vision coverage
• 401(k) matching and stock allocation
• 4 weeks of paid sabbatical after 5 years of service
• Daily lunch provided for onsite employees
• Opportunities for professional growth and career development in a fast-paced, mission-driven biotech environment

Equal Opportunity Employer

Predicine is proud to be an Equal Opportunity Employer, committed to a diverse and inclusive workplace. All qualified applicants will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability, or any other legally protected status. Qualified applicants will also be considered regardless of criminal history, consistent with applicable law.

Compensation is based on qualifications, location, internal equity, and market data. All offers are contingent upon successful background verification. Applicants must be legally authorized to work in the USA without sponsorship.

We are not accepting third-party resumes from recruiters, recruiting agencies, or third-party vendors.