Moslehi Lab - Junior Specialist

University of California, San Francisco; San Francisco (CA); On-site; USD 55,000 - 58,600; Full time

Job summary

The Moslehi Lab at UCSF is seeking a Junior Specialist to advance projects on cardiovascular toxicities linked to cancer therapies. You will work with pre-clinical mouse models and cell-based systems to study immune-oncology–related cardiac effects.

You will gain hands-on experience with flow cytometry, western blotting, single-cell RNA sequencing, and bioinformatic analysis using Seurat/R, and may contribute to translational and clinical projects to inform cardio-oncology care.

Qualifications

• B.A. in biology or related topic, or equivalent research experience.
• Self-motivated and able to learn quickly.
• Effective communication skills and the ability to collaborate with team members toward broader laboratory goals.
• Proven ability to manage time, work on multiple concurrent projects, and meet deadlines.
• Ability to conduct literature reviews and contribute to manuscript preparation or revision.

Skills

Self-motivation

Communication skills

Time management

Collaboration

Literature review

Education

Bachelor's degree in biology or related field

Tools

Flow cytometry

Western blotting

Single-cell RNA sequencing

Bioinformatic analysis (Seurat/R)

Job description

Position Description

The Moslehi Lab is recruiting for a Junior Specialist. The incumbent will pursue several projects related to the growing concerns of cardiovascular toxicities associated with cancer immunotherapies and other chemotherapeutic drugs. We are generating and characterizing pre‑clinical mouse models that recapitulate the cardiovascular toxicities associated with novel cancer immunotherapies, such as immune checkpoint inhibitor myocarditis, and using these models to elucidate underlying cardiovascular and immunological biology. These scientific observations are coupled with a robust clinical surveillance program. The incumbent will help in better characterizing these pre‑clinical models, including both cell‑based and small‑animal models, and may also assist in the translational and clinical projects of the Moslehi Lab and the UCSF Cardio‑Oncology Section. The goal is to inform clinical care for the expanding cardio‑oncology patient population.

The incumbent will gain experience in molecular biology techniques such as flow cytometry, western blotting, single‑cell/single‑nucleus RNA sequencing, and will contribute to bioinformatic analysis of sequencing data on platforms such as Seurat/R. The role also involves working with mouse models and related animal analyses such as ECG and echocardiogram.

Required Qualifications

• B.A. in biology or a related topic, or equivalent research experience.
• Self‑motivated and able to learn quickly.
• Effective communication skills and the ability to collaborate with team members toward broader laboratory goals.
• Proven ability to manage time, work on multiple concurrent projects, and meet deadlines.
• Ability to conduct literature reviews and contribute to manuscript preparation or revision.

Preferred Qualifications

• Previous experience with mouse handling and/or colony maintenance.
• Previous flow cytometry experience.
• Working knowledge of Seurat/R.
• Interest in cardio‑oncology or immunology.

Compensation and Benefits

Salary is commensurate with experience and training. A reasonable estimate for this position is $55,000-$58,600. (See Table 24B for the salary range.)

Location: San Francisco, CA

Equal Employment Opportunity

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law. UCSF is committed to welcoming and serving all people, honoring the dignity of every individual without preference or prejudice, in support of its public mission and in alignment with our PRIDE values and Principles of Community.