Molecular Technologist I-III

Tempus AI; Minneapolis (MN); On-site; USD 32,000 - 41,000; Full time

Job summary

OneOme is seeking a Molecular Technologist to work closely with laboratory staff and cross‑functional teams in support of pharmacogenomics testing operations. This role is responsible for several phases of the testing workflow, including sample accessioning, DNA extraction, real‑time PCR, and data analysis.

The Molecular Technologist performs high‑complexity clinical molecular testing in accordance with established procedures, quality standards, and regulatory requirements.

Qualifications

• Bachelor’s degree in Medical Technology or related biology field.
• At least 3 years of laboratory experience with molecular testing.
• Experience with DNA extraction, real‑time PCR, and SNP genotyping.
• Knowledge of laboratory automation and validation activities.
• Strong attention to detail and accuracy.
• Effective written and verbal communication.
• Ability to work in a fast‑paced, cross‑functional environment.

Responsibilities

• Perform sample accessioning, DNA extraction, PCR testing, and data review per SOPs.
• Conduct high‑complexity clinical molecular testing per regulations and quality standards.
• Perform quality control and quality assurance activities, record maintenance, and audits.
• Support assay development, workflow optimization, validations, and software verification testing.
• Develop written technical content for procedures and white papers.
• Assist with clerical duties, inventory control, client service tasks, and other responsibilities.
• Collaborate with laboratory staff and other departments to support operational excellence.
• Maintain flexibility to cover weekend shifts.

Skills

Molecular testing

Lab automation

PCR real-time

DNA extraction

Attention to detail

Communication skills

Team collaboration

Education

Bachelor’s degree in Medical Technology/Clinical Laboratory Sciences

Biology or related field acceptable

Tools

Liquid handling systems

In-house assay development

Primer/probe design

Job description

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Job Description

OneOme is seeking a Molecular Technologist to work closely with laboratory staff and cross‑functional teams in support of our pharmacogenomics testing operations. This role is responsible for several phases of the testing workflow, including sample accessioning, DNA extraction, real‑time PCR, and data analysis. The Molecular Technologist performs high‑complexity clinical molecular testing in accordance with established procedures, quality standards, and regulatory requirements.

In addition to routine clinical testing, this position will contribute to assay development and validation, quality assurance and quality control activities, and other laboratory initiatives as assigned by the Director of Laboratory Operations. The ideal candidate will bring strong technical expertise, excellent attention to detail, effective communication skills, and the ability to work both independently and collaboratively in a fast‑paced environment. This role is expected to support operational needs that include weekend shifts.

SHIFT - Tuesday-Saturday (9:00am-5:30pm)

Responsibilities

• Perform sample accessioning, DNA extraction, PCR testing, and data review according to standard operating procedures
• Conduct high‑complexity clinical molecular testing in compliance with applicable regulatory and quality standards
• Perform quality control and quality assurance activities, including maintenance of associated records, monthly and annual reviews, and internal audits
• Support laboratory development activities, including new method and assay development, workflow and process optimization, analytical validations, and software verification testing
• Develop written technical and scientific content for procedures, policies, white papers, and peer‑reviewed publications
• Assist as needed with non‑laboratory functions, including clerical duties, inventory control, client service activities, and other assigned responsibilities
• Collaborate effectively with laboratory staff and other departments to support operational excellence
• Maintain flexibility to support scheduled weekend coverage as needed

Required Qualifications

• Bachelor’s degree in Medical Technology, Clinical Laboratory Sciences, or another biological science such as Biology
• Minimum of 3 years of laboratory experience, including at least 1 year in a molecular testing laboratory environment
• Working knowledge of molecular biology analytical techniques, including DNA isolation, real‑time PCR, and SNP genotyping, preferably in the area of pharmacogenomics
• Experience with laboratory automation and liquid handling systems, in‑house assay development, and validation activities including primer and probe design, assay optimization, and troubleshooting
• Strong attention to detail and ability to follow stringent procedures with a high degree of accuracy
• Effective written and verbal communication skills
• Ability to work successfully in a fast‑paced environment and collaborate across multiple disciplines

Preferred Qualifications

• ASCP certification, or eligibility for certification in a related specialty
• Prior experience in a CLIA laboratory environment
• 4 years of experience performing high‑complexity testing
• Experience working in a small, fast‑paced, or start‑up environment

MIN: $23-30/hr

The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.