Molecular Epidemiology, Sequencing and Bioinformatics Manager

State of North Carolina; Wake Forest (NC); On-site; USD 83,000 - 137,000; Full time

Benefits offered by this job

Fitness area

Career development classes

On-site amenities

Library of academic journals

Job summary

The NC Department of Health and Human Services’ Molecular Epidemiology, Sequencing and Bioinformatics group seeks a Medical Laboratory Supervisor III to manage complex molecular testing and surveillance operations. You will oversee sequencing, bioinformatics workflows, and a multidisciplinary team to support diagnostic testing and epidemiological investigations.

Candidate must hold a bachelor’s degree in medical technology or a related field and have four years of lab experience, including two

Qualifications

• Bachelor’s degree in medical technology, chemistry, or a biological science.
• Four years of experience in a laboratory in the assigned area, two of which are supervisory.

Responsibilities

• Perform complex molecular testing including next-generation sequencing and real-time PCR.
• Direct characterization of agents from clinical, reference, and environmental specimens.
• Oversee bioinformatics workflows and sequencing data analysis.
• Supervise a multidisciplinary team in sequencing operations and molecular surveillance.
• Coordinate QA, staffing, SOP development, and LIMS operations.
• Implement workflows supporting diagnostic testing and epidemiological investigations.

Skills

NGS sequencing

Real-time PCR

Molecular surveillance

Laboratory leadership

Bioinformatics workflows

Education

Bachelor's degree in medical technology/biological sciences

Tools

Laboratory information management systems

Job description

Agency

Dept of Health and Human Services

Division

Public Health

Job Classification Title

Medical Laboratory Supervisor III (NS)

Position Number

60041391

Grade

MH20

About Us

The North Carolina Department of Health and Human Services (DHHS) is one of the largest, most complex agencies in the state, and has approximately 17,000 employees. It is responsible for ensuring the health, safety, and well-being of all North Carolinians, providing human service needs for special populations including individuals who are deaf, blind, developmentally disabled, and mentally ill, and helping poor North Carolinians achieve economic independence.

Description of Work

The Molecular Epidemiology, Sequencing and Bioinformatics Manager manages a multidisciplinary team within the Molecular Epidemiology, Sequencing and Bioinformatics group at the NC State Laboratory of Public Health, overseeing highly complex molecular testing used to detect, identify, and monitor pathogens of public health significance. The position directs routine sequencing and molecular surveillance activities, bioinformatics workflows, and advanced molecular detection methods that support diagnostic testing and epidemiological investigations.

Work includes coordinating method development, evaluation, and implementation of new technologies while maintaining quality assurance, procurement, staffing, and laboratory information management functions. This role serves as a resource to internal and external partners and contributes to statewide and regional surveillance efforts as part of the senior leadership team.

Key Duties Include:

• Perform complex molecular testing, including next‑generation sequencing, real‑time PCR, and advanced molecular detection methods to identify pathogens.
• Direct characterization of agents from clinical, reference, and environmental specimens using high‑complexity laboratory procedures.
• Oversee bioinformatics workflows, including data analysis, infrastructure maintenance, and sequencing workflow software.
• Supervise a multidisciplinary team conducting molecular surveillance, routine sequencing, and method development.
• Coordinate procurement, quality assurance, staffing, SOP development, and laboratory information management system operations.
• Implement and refine laboratory workflows supporting diagnostic testing, epidemiological investigations, and surveillance.
• Serve as a technical resource to internal teams, external partners, and regional collaborators, including activities related to advanced molecular detection training.
• Ensure compliance with federal regulations and accreditation standards across all molecular and sequencing operations.
• Collaborate with communicable disease epidemiologists and partner agencies to support statewide public health priorities.
• Support implementation of strategic initiatives by working with leadership to advance the group’s long‑term vision.

Knowledge Skills and Abilities/Management Preferences

_ Salary Grade Range: $82,857.00 - $136,714.00 _

_ Recruitment Range: $82,857.00 - $106,723.00 _

Candidates now meet the minimum qualifications of a position if they meet the minimum education and experience listed on the vacancy announcement.

The Knowledge, Skills, and Abilities (KSAs)/ Management Preferences are not required. Applicants who possess the following skills are preferred:

• Expert proficiency performing highly complex molecular testing workflows such as next‑generation sequencing, real‑time PCR, and advanced molecular detection methods used for pathogen identification.
• Demonstrated experience managing sequencing and bioinformatics pipelines, including routine analysis tasks, workflow coordination, and maintenance of computational tools supporting molecular surveillance.
• Strong track record directing multidisciplinary laboratory teams engaged in sequencing operations, molecular surveillance, and development of new testing methods.
• Proven success coordinating laboratory quality assurance processes, procurement activities, staffing plans, and development and maintenance of standard operating procedures within a high‑complexity molecular testing environment.
• Advanced skill using sequencing workflow management and analysis software to support diagnostic testing, pathogen characterization, and large‑scale molecular surveillance initiatives.

The Posting Will Close At 11:59 P.M. The Night Before The End Date

Employees In This Position Must Be Capable Of Meeting The Federal CLIA ’88 Personnel Requirements Of Testing Personnel In A Laboratory Performing High Complexity Testing. Applicants Must Attach Copies Of Their Transcript(s) And / Or Certification(s) To Be Considered For The Position

About the NC Division of Public Health (DPH):

The NC Division of Public Health works to promote and contribute to the highest possible level of health for the people of North Carolina. Our entire statewide system of public health has dedicated professionals who carry out our mission every day through a wide range of essential and activities touching the lives of everyone in our state.

About the Molecular Epidemiology, Sequencing and Bioinformatics Group:

The Molecular Epidemiology, Sequencing and Bioinformatics group is responsible for performing a variety of highly complex laboratory tests to identify human pathogens of public health significance. The reports generated by this group are used by state and local health officials in the detection, identification and surveillance of pathogens. The tests performed in this group are primarily molecular-based such as next generation sequencing (NGS), real‑time PCR, and other advanced molecular detection methods. The group conducts highly complex procedures for the identification and characterization of a wide range of agents from a variety of clinical, reference, and environmental specimens and utilizes bioinformatic analyses when applicable. This group serves as a resource to internal and external partners, other units within the NC SLPH, and in the Mid‑Atlantic region as an Advanced Molecular Detection (AMD) Training Co‑Lead with the Virginia Department of Consolidated Laboratory Services (VA DCLS).

Campus Amenities and Benefits at the State Laboratory of Public Health:

• 220,000 square feet state‑of‑the‑art facility
• Plentiful Free Parking
• Easy access to highways (70, 40 and 440), NC Museum of Art, Umstead State Park, healthcare providers, and shopping centers
• Proximity to globally and nationally ranked universities (NC State, UNC‑Chapel Hill, Duke)
• Fitness area with exercise equipment, classes, and wellness activities
• Weekly Food Trucks
• Car Cleaning and Detailing Services On‑site bimonthly
• Annual Flu Shot Clinic for Employees and Families
• Monthly and quarterly career development classes, including opportunities for traveling
• Library of academic journals and materials on‑site
• Employee Engagement and Staff Development Activities
• NCSLPH Employee Recognition Programs
• State Health Plan and State of NC Employee Benefits

Compensation and Benefits:

The State of North Carolina offers excellent comprehensive benefits. Employees can participate in health insurance options, standard and supplemental retirement plans, and the NCFlex program (numerous high‑quality, low‑cost benefits on a pre‑tax basis). Employees also receive paid vacation, sick, and community service leave. In addition, paid parental leave is available to eligible employees.

Visit the website for State Benefits.

Supplemental Contact Information:

The North Carolina Department of Health and Human Services (DHHS) is an Equal Opportunity Employerthat embraces an Employment First philosophy, which consists of complying with all federallaws, state laws, and Executive Orders. We are committed to reviewing requests for reasonable accommodation at any time during the hiring process or while on the job. For more information about DHHS: https://www.ncdhhs.gov/.

DHHS uses the Merit‑Based Recruitment and Selection Plan to fill positions subject to the State Human Resources Act with the most qualified individuals. Hiring salary will be based on relevant qualifications, internal equity, and budgetary considerations pertinent to the advertised position.

In accordance with the Governor’s Executive Order 303, our agency supports second‑chance employment for individuals who were previously incarcerated or justice‑involved. We invite all potential applicants to apply for positions for which they may be qualified.

Contact:

DHHS Workday Support Form

Minimum Education and Experience

Some state job postings say you can qualify by an “equivalent combination of education and experience.” If that language appears below, then you may qualify through EITHER years of education OR years of directly related experience, OR a combination of both. See the Education and Experience Equivalency Guide for details.

Bachelor’s degree in medical technology, chemistry, or a biological science from an appropriately accredited institution and four years of experience in a laboratory in the assigned area, two of which is in a supervisory capacity

OR

An equivalent combination of education and experience.

EEO Statement

The State of North Carolina is an Equal Employment Opportunity Employer and dedicated to providing employees with a work environment free from all forms of unlawful employment discrimination, harassment, or retaliation. The state provides reasonable accommodation to employees and applicants with disabilities; known limitations related to pregnancy, childbirth, or related medical conditions; and for religious beliefs, observances, and practices.