Mithrl - Senior/Staff Full Stack Engineer

deCircle; San Francisco (CA); On-site; USD 150,000 - 210,000; Full time

Job summary

Mithrl is hiring a Senior/Staff Full Stack Engineer to join its SF-based engineering team. You will build features across frontend and backend, design scalable services, and own end-to-end delivery to researchers at top pharma/biotech companies.

The role emphasizes rapid production contributions, collaboration with AI scientists, and shaping foundational systems for a growing platform.

Qualifications

• 10+ years of professional full-stack or backend engineering (excluding internships).
• Builder excited to create foundational systems from scratch.
• Python/Django, React, GraphQL, SQL, REST APIs; AWS/GCP/Azure.
• 5 days in-person in San Francisco (Montgomery BART; flexible).
• No biology background needed.

Responsibilities

• Build new product features and systems from scratch across frontend and backend, expanding Mithrl's platform for world-class researchers
• Design, build, and own scalable backend services, APIs, and data pipelines across the application, identity, data storage, and ML layers
• Work in fast-moving sprint cycles, contributing to production within your first few weeks
• Collaborate with engineers, PMs, designers, and AI scientists to turn complex scientific workflows into intuitive, high-performance software
• Own features end-to-end from development through production deployment, iteration, and scale for researchers at leading pharma and biotech organizations

Skills

Full-stack development

Backend development

System design

Collaborative skills

Technical leadership

Tools

Python

Django

React

GraphQL

SQL

REST APIs

AWS

GCP

Azure

Job description

Source: Paraform - https://www.paraform.com/share/mithrl/cmo8wm449000k0cjyi5yl30gw

Compensation: not listed on the public Paraform page (check Paraform login).

Location: San Francisco, CA - on-site 5 days/week (flexible), near Montgomery BART. Visa: open to transfers (OPT, H1B).

About this role

Senior/Staff Full Stack Engineer with 10+ YOE to join Mithrl's engineering team: a builder excited to create foundational systems and have meaningful influence on the technology as Mithrl accelerates drug discovery. Top-priority hire driven by hypergrowth and surging enterprise demand.

Responsibilities

• Build new product features and systems from scratch across frontend and backend, expanding Mithrl's platform for world-class researchers

• Design, build, and own scalable backend services, APIs, and data pipelines across the application, identity, data storage, and ML layers

• Work in fast-moving sprint cycles, contributing to production within your first few weeks

• Collaborate with engineers, PMs, designers, and AI scientists to turn complex scientific workflows into intuitive, high-performance software

• Own features end-to-end from development through production deployment, iteration, and scale for researchers at leading pharma and biotech organizations

Tech stack

Python, Django, React, GraphQL, AWS, GCP, Azure, SQL, REST APIs

About Mithrl

AI Co-Scientist / scientific decision engine for pharma and biotech R&D: turns unstructured biological data (omics, sequencing) into analysis, novel targets and patent-ready reports in minutes, powered by a proprietary biological knowledge graph. 12x YoY revenue growth; customers include J&J, Roche, Eli Lilly, AstraZeneca and Siemens. ~25 people in person in SF; founded 2023; $80M total funding (Series A led by Obvious Ventures). Engineering ~10, growing to 30 this year.

• 10+ years of professional full-stack or backend engineering (excluding internships)

• Builder excited to create foundational systems from scratch

• Python/Django, React, GraphQL, SQL, REST APIs; AWS/GCP/Azure

• 5 days in-person in San Francisco (Montgomery BART; flexible)

• No biology background needed