METABOLIC ENGINEER

Polyose Bio; Boston (MA); On-site; USD 120,000 - 190,000; Full time

Job summary

Polyose Bio in Boston is seeking researchers to optimize metabolic flux in sugar polymer biosynthesis through fermentation and computational methods. You will collaborate with Synthetic Biology and Polymer Chemistry teams to improve production strains and methods, while documenting results and contributing to IP generation.

Ideal candidates hold a PhD or MSc in Chemical/Biological Engineering or related fields, with 3+ years of lab experience and strong fermentation and metabolic modeling

Qualifications

• PhD or MSc in Chemical/Biological Engineering or related fields.
• 3+ years of research experience in an academic or industry lab.
• Experience in fermentation and metabolic modeling (FBA, COBRA, OptFlux).

Responsibilities

• Develop computational methods to optimize metabolic flux through sugar polymer biosynthesis pathways.
• Create experimental workflows to perform fermentation and collect data.
• Collaborate with the Synthetic Biology and Polymer Chemistry teams to optimize sugar polymer biosynthesis pathways in production strains.
• Communicate methods and results both internally and externally with scientists, executives, and researchers.
• Contribute to generation and documentation of intellectual property.

Skills

Computational methods

Fermentation

Experimental workflows

Collaborative work

Scientific communication

IP documentation

Education

PhD or MSc in relevant field

Tools

FBA

COBRA

OptFlux

Job description

We will use metabolic engineering applications to optimize the metabolic flux through sugar polymer biosynthesis pathways, and improve product yields during fermentation.

LOCATION

Boston

EMPLOYMENT TYPE

Full-time and Internship

What You’ll Do

• Develop computational methods to optimize metabolic flux through sugar polymer biosynthesis pathways.
• Create experimental workflows to perform fermentation and collect data.
• Collaborate frequently with the Synthetic Biology and Polymer Chemistry teams to optimize sugar polymer biosynthesis pathways in the production strains.
• Communicate methods and results both internally with the team and externally with other scientists, industry executives, and academic researchers.
• Contribute to the generation and documentation of intellectual property

Who You are

• Passionate about sustainability
• Excited to be part of a fast-paced startup
• Ph.D. or M.Sc. in Chemical or Biological Engineering, Fermentation, or related fields.
• 3+ years of research experience in an academic or industry lab setting.
• Skilled in fermentation, and computational methods such as FBA, COBRA, and OptFlux.
• Ability to work both independently and in a collaborative team environment.
• Metabolomic data analysis expertise.
• Experience in synthetic biology and sugar polymer biosynthesis is a plus.