MES Specialist

Scorpion Therapeutics; Pennsylvania; On-site; USD 90,000 - 130,000; Full time

Job summary

Scorpion Therapeutics seeks an MES Specialist to oversee manufacturing execution and automation across the site. You will develop MES/EBR solutions, configure recipes, and ensure cross-functional integration with production, quality control, and data systems.

You will ensure GMP compliance, assist in vendor selection, risk management, and provide training and post-implementation support to operations teams. Collaboration with QC, Facilities, and Tech Transfer is key to success.

Qualifications

• Bachelor’s degree or equivalent in engineering/biopharma.
• 1+ years MES/EBR and automation experience in biopharma or related industry.
• Familiarity with process control systems (DeltaV/Aveva/PLCs).

Responsibilities

• Oversee MES and automation across the site.
• Develop MES/EBR solutions including recipes and configurations.
• Ensure integration with production, QC, and data management systems.

Skills

Siemens OpCenter

DeltaV

Aveva

OPC

PLCs

Education

Bachelor’s degree in engineering/biopharma

Tools

Historian

ERP connectivity

Job description

Main Responsibilities:

• Oversee manufacturing execution system (MES) and automation within the whole site.

Key Responsibilities:

• Develop MES/Electronic Batch Record (EBR) solutions, including recipe and configuration/system changes, to meet business requirements.
• Ensure system integration with digital applications supporting production, quality control, and data management.
• Ensure GMP and regulatory compliance (C&Q): develop specifications, test protocols, and support system validation; tailor strategies via site assessments.
• Coordinate with procurement and project teams to select manufacturing systems/automation vendors aligned to quality and regulatory standards.
• Identify and proactively manage risks; maintain GMP compliance to minimize timeline/cost disruptions.
• Develop and deliver training for operations staff; provide ongoing post-implementation support and mentorship for new MES Specialists.
• Collaborate with Manufacturing, Supply Chain, Quality, Facilities, and Tech Transfer to capture/document requirements; provide MES application support as needed.
• Develop best practices/standards; lead design reviews and user acceptance testing during change/validation.
• Plan, develop, peer review, test, and implement recipe creation/modification and other MES changes.
• Participate in facility operational meetings to meet reporting needs.
• Provide rotating on-call support during off-shift hours.

Qualifications:

• Bachelor’s degree in engineering (Electrical/Chemical/Mechanical/Automation), Computer Science, Biotechnology, Health Sciences, or related biopharma field.
• 1+ years’ experience supporting MES/EBR and automation in biopharma or related industries.

Required/Technical Skills:

• Hands-on MES Siemens OpCenter; DCS (DeltaV), SCADA (Aveva), PLCs.
• Familiarity with process control systems (DeltaV, Aveva, PLCs).
• Machine connectivity/data acquisition from PLCs to Historian/ERPs using technologies such as OPC.

Technical Skills:

• MES platform configuration (Siemens OpCenter); EBR support; DCS/SCADA (DeltaV, Aveva); OPC/data integration (Historian, ERP connectivity).

Soft Skills:

• Technical/project leadership, collaboration, analytical skills, and communication with cross-functional teams.