Member of Technical Staff - Biostatistics

Edison Scientific; United States; On-site; USD 180,000 - 250,000; Full time

Benefits offered by this job

Competitive salary and equity

Full healthcare coverage

Parental leave and family support

Mental health support

401(k) matching

Commuter benefits

Team off-sites and events

Job summary

Edison Scientific is seeking a Forward-Deployed Biostatistics Subject Matter Expert to build and evaluate AI agent systems for statistical analysis and clinical development workflows. You will be embedded with leading pharma and biotech organizations, ensuring regulator-ready outputs and advancing SAP development, trial design, and submission-quality deliverables.

Ideally based in Boston, NYC, or San Francisco, or fully remote with 20-40% travel, you will collaborate with biostatisticians,

Qualifications

• 5+ years of biostatistics experience in biotech or pharma (sponsor or CRO).
• Ph.D. in Statistics or Biostatistics preferred.
• Proven SAP crafting, sample size, and early-phase trial design.
• Proficiency in R and/or SAS (both preferred).
• Experience in oncology, immuno-oncology, immunology, cardiovascular, neurology, or hepatology.
• Deep knowledge of ICH/FDA regulatory standards, CSRs, INDs, and CDISC standards (SDTM/ADaM).
• Prior industry or client-facing experience outside academia.
• Willingness to travel domestically 20-40%.

Responsibilities

• Improve LLM agents for long, coherent statistical analysis and trial design tasks within real-world scientific environments and customer data infrastructures.
• Design benchmarks to evaluate LLM agent performance, acceptance criteria, and failure modes on complex biostatistical tasks.
• Partner directly with biostatisticians and clinical development leaders at client organizations to apply AI agents to statistical and regulatory deliverables.
• Serve as the statistical authority on AI-generated outputs, evaluating accuracy and regulatory soundness, identifying failure modes, and determining what warrants further investigation.
• Partner with GTM and account executives to scope engagements, define success metrics, and support pre-sales technical evaluation.
• Build trusted relationships with biostatisticians and research leaders at customers, earning credibility as both a statistical peer and a knowledgeable AI practitioner.

Skills

5+ years biostatistics experience

SAP development

Sample size determination

Clinical trial design (I/II)

ICH/FDA regulatory knowledge

Industry/client-facing experience

Travel 20-40%

Education

Ph.D. in Statistics/Biostatistics or related

Tools

R

SAS

Python

Job description

About Us

Edison Scientific builds and deploys AI scientist agents to accelerate science and the development of new medicines. We are an ambitious team run by scientists and engineers from leading institutions across biology, physics, chemistry, and AI.

About Us

Edison Scientific builds and deploys AI scientist agents to accelerate science and the development of new medicines. We are an ambitious team run by scientists and engineers from leading institutions across biology, physics, chemistry, and AI.

Role

As a Forward-Deployed Biostatistics Subject Matter Expert, you will build and evaluate AI agent systems to automate statistical analysis and clinical development workflows. You'll be embedded directly with some of the world's leading pharma and biotech organizations, and will be responsible for ensuring Edison's AI agents deliver statistically sound, regulator-ready outputs. You'll work with our partners to create benchmarks that measure agent performance on complex tasks across trial design, SAP development, and submission-quality statistical deliverables, then work with our internal AI engineering team to improve agent performance on those tasks. You'll need to deeply understand our partners' statistical methodology, their study design conventions, and their regulatory bar, then determine where our platform can drive the most meaningful impact.

This position would ideally be in Boston, NYC or San Francisco, but we are also open to fully remote with 20-40% travel.

Responsibilities

• Improving the ability of LLM agents to execute long, coherent statistical analysis and trial design tasks within real-world scientific environments and customer data infrastructures.
• Designing benchmarks to evaluate LLM agent performance, acceptance criteria, and failure modes on complex biostatistical tasks (e.g., SAP development, sample size determination, endpoint analysis).
• Partnering directly with biostatisticians and clinical development leaders at client organizations to apply AI agents to statistical and regulatory deliverables.
• Serving as the statistical authority on AI-generated outputs, evaluating accuracy and regulatory soundness, identifying failure modes, and determining what warrants further investigation.
• Partner with GTM and account executives to scope engagements, define success metrics, and support pre-sales technical evaluation.
• Build trusted relationships with biostatisticians and research leaders at customers, earning credibility as both a statistical peer and a knowledgeable AI practitioner.

Requirements

• 5+ years of experience in biostatistical applications within biotech or pharma (sponsor or CRO).
• Graduate degree (Ph.D. preferred) in Statistics, Biostatistics, or a related discipline.
• Proven expertise in crafting SAPs, determining sample sizes, and designing early-phase (I/II) clinical trials.
• Proficiency in R and/or SAS (both preferred).
• Experience in therapeutic areas such as oncology, immuno-oncology, immunology, cardiovascular, neurology, or hepatology (MASH) preferred.
• Deep familiarity with ICH and FDA regulatory standards, including direct experience with CSRs, IND filings, and CDISC-compliant datasets (SDTM/ADaM).
• Prior experience in an industry or client-facing context, outside of academia.
• Ability to travel domestically 20-40% of the time.

Bonus points for

• Proficiency in Python and/or TypeScript/JavaScript.
• You enjoy quickly iterating on ideas through rapid prototyping.
• You operate with high independence, and like to execute complex tasks to completion in a high-stakes environment.
• You thrive when working on a diversity of projects in sprint-based formats, and have high comfort with uncertainty.
• You are proficient in statistical programming and validation, and could QC or independently reproduce an analysis if necessary.

Why join us?

We're a Fast-moving, Mission-driven Culture Where Smart People Do Their Best Work And Actually Enjoy Doing It. We Also Offer Full-time Employees The Following

• Competitive salary and equity
• Full healthcare coverage; we pay 100% of premiums for you and your dependents
• Support for growing families, including a yearly new parent stipend and fertility coverage through Carrot
• Mental health support through Rula, our in-network therapist and psychiatrist network with fast availability
• 12 weeks of paid parental leave for maternity, paternity, and adoption
• Pet care support with a yearly employer-funded stipend for your animal companions
• Commuter benefits so you can pay for transit and parking with pre-tax dollars
• 401(k) company matching
• $300 health and wellness benefit quarterly
• Lunch is on us every day you're in the office, and dinner is on us when you're working late
• Regular team off-sites and company events

Edison Scientific is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected characteristic under applicable law.

Compensation Range: $180K - $250K