Medical Oncologist/Principal Investigator

The START Center for Cancer Research; Charlotte (NC); On-site; USD 180,000 - 300,000; Full time

Benefits offered by this job

401(k) retirement savings plan withem​

Annual performance bonus

Paid time off and holidays

Medical, dental, and vision coverage

Life and disability insurance

Employee Assistance Program

Flexible FSA and HSA

Job summary

The START Center for Cancer Research in Charlotte, NC, seeks a Clinical Principal Investigator to lead early-phase oncology trials, oversee protocol development, regulatory compliance, and sponsor communications, and provide expert data interpretation with a multidisciplinary team.

The role requires an MD, board certification in hematology/oncology, and extensive trial experience focused on drug development, patient safety, and ethics. On-site schedule is M-F 8a-5p.

Qualifications

• MD or equivalent qualification.
• Board certified in hematology and/or medical oncology.
• Clinical trials experience with strong drug development interest.
• Understanding of GCP principles, safety reporting, FDA regulations, and biomedical ethics.
• Commitment to collaborative, patient-centered care.

Responsibilities

• Provide medical direction and reviews of protocols in line with the investigational plan and GCP.
• Lead early phase oncology trial conduct.
• Ensure safety and rights of trial participants are protected.
• Ensure data collected at the site is credible and accurate.
• Develop relationships with sponsors and CROs involved in study conduct.
• Support clinical operations staff and sponsor client.
• Lead continuous quality improvement in clinical research services.
• Develop and implement patient recruitment and retention strategies.

Skills

Communication skills

Data analysis

GCP knowledge

Team player

Education

MD or equivalent

Board Certified in Hematology/Medical Oncology

Job description

The START Center for Cancer Research (“START”) is the world’s largestearly phasesite network, fully dedicated tooncologyclinical research.Throughout ourhistory, START has provided hope to cancer patients inglobalcommunity practices by offering"Hope Through Access"tocutting edgetrials throughout the UnitedStatesand Europe.

We are seeking a Clinical Principal Investigator. The Clinical Principal Investigator (PI) is a physician-scientist responsible for the overall preparation, conduct, and management of sponsored projects, ensuring compliance with all regulatory requirements and institutional policies. This role will manage the development and execution of clinical trial protocols, contribute to data analysis, and maintain strong communication and alignment with sponsors.

Schedule: M-F 8a-5p

Location: 125 Queens Rd.Charlotte, North Carolina28204

Essential Responsibilities

• Manage early phase clinical trials by providing overarching medical direction and comprehensive medical reviews of protocols in conformance with the investigational plan and good clinical practice.
• Provide medical and scientific feasibility of all new sponsor inquiries driving growth through strategic partnerships.
• Lead and manage a matrix team of responsible for responsible for the conduct of early phase oncology trials.
• Ensure the safety and well-being of all participants in the study at the trial site are protected.
• Ensure data collected at the study site is credible and accurate.
• Ensure the rights, integrity, and confidentiality of all participants in the trial at the site are protected.
• Develop close personal working relationships with Sponsors and Clinical Research Organizations involved in study conduct.
• Provide expert guidance and support to clinical operations research staff and sponsor client.
• Lead continuous quality improvement efforts for clinical research services, integrating best practices and fostering a culture of research excellence.
• Develop and implement strategies to enhance patient recruitment and retention in clinical trials.

Required Education and Experience

• M.D. or equivalent.
• Board Certified in Hematology and/or Medical Oncology.
• Clinical trials experience with a strong interest in drug development.
• Ability to critically analyze clinical scientific data and literature.
• Understanding of GCP principles, safety and adverse event reporting, FDA regulations, and biomedical research ethics.
• A passion for providing excellent clinical care and for working in a collaborative / team-oriented environment.

Preferred Education and Experience

• Previous experience with industry sponsored clinical trials.
• Excellent communication skills, with experience in publishing and presenting at scientific meetings.
• Translational research experience and familiarity with pharmacokinetics and pharmacodynamics.

Potential applicants should directly contact Mary Vidovich ( [e-mail] ) or Chris H. Takimoto, MD, PhD ( [e-mail] ) at START Research

Best-in-Class Benefits and Perks

We value the time, talent, and dedication our employees bring to START. Our commitment to yourwell-beingand growth is reflected in a competitive compensation package—based on experience—along with comprehensive benefits designed to support you both personally and professionally:

• 401(k) retirement savings plan with employer match
• Eligibility for an annual performance bonus, based on role and company results
• Generous paid time off and paid holidays
• Comprehensive medical, dental, and vision coverageand optional insuranceoptions
• Company paid life and disability insurance for added financial protection
• Employee Assistance Program (EAP) providing confidential, no‑cost support for you and your family from day one
• Flexible FSA and HSA plans to support your financial wellness
• Commitment to a supportive environment that values balance, wellbeing, and flexibility
• We’re committed to fostering a collaborative, creative workplace where every team member is encouraged to contribute. At START,you’lljoin a team that values continuous learning, professional growth, shared ideas, and a culture built on inclusivity and innovation.

More About START

START clinical trial sites have conducted more than 1,000 early-phase clinical trials, including dozens of therapies that were approved by the FDA or EMA. STARTrepresentsthe world’s largest roster of early-phase principal investigators across its Network of clinical trial sites.

Learn more at STARTresearch.com .

Ready to be part of a team changing the future of cancer treatment?

Join us in our mission to conquer cancer, one clinical trial at a time. Yourexpertiseand dedication can help us bring hope and healing to patients worldwide.

We are an equal opportunity employer that welcomes and encourages diversity in the workplace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.