Medical Director - Immuno-Oncology (Early-Stage Trials)

IntePros; Boston (MA); On-site; USD 150,000 - 250,000; Full time

Job summary

An innovative clinical-stage biotech company is on the lookout for a Medical Director to spearhead the early-phase clinical development of a groundbreaking immunotherapy targeting solid tumors. This pivotal role involves designing and overseeing clinical trials, ensuring patient safety, and engaging with regulatory bodies. The ideal candidate will have extensive experience in immuno-oncology trials and a proven track record in developing first-in-human protocols. Join a dynamic team that is committed to advancing cutting-edge therapies and making a significant impact in the field of oncology. If you're ready to lead and innovate, this opportunity is for you.

Qualifications

• 5-6+ years leading early-phase immuno-oncology trials in biotech or pharma.
• Strong leadership and regulatory strategy experience required.

Responsibilities

• Design and oversee Phase I/II clinical trials for immunotherapy.
• Serve as Medical Monitor and ensure patient safety.

Skills

Leadership

Cross-functional collaboration

Regulatory strategy

Clinical trial design

Immuno-oncology expertise

Job description

Medical Director - Immuno-Oncology (Early-Stage Trials)

Contract: 12 months (with potential for extension)

A clinical-stage biotech company is seeking a Medical Director to lead the early-phase clinical development of a novel immunotherapy targeting solid tumors. This is a hands-on role with strategic influence, overseeing protocol design, trial execution, medical monitoring, and regulatory engagement for a first-in-human (FIH) study.

Key Responsibilities:

• Design and oversee early-phase (Phase I/II) clinical trials, including dose escalation/expansion strategies
• Serve as Medical Monitor, ensuring patient safety and informed clinical decision-making
• Collaborate cross-functionally with clinical ops, research, and regulatory teams
• Lead and participate in Safety Review Committees and external stakeholder meetings
• Draft and review key IND-enabling and clinical regulatory documents
• Translate non-clinical and translational findings into adaptive clinical plans

Qualifications:

• 5–6+ years’ experience leading early-phase immuno-oncology trials in biotech/pharma
• Deep understanding of biologics-based immunotherapies
• Proven ability to develop and execute FIH protocols
• Strong leadership, cross-functional collaboration, and regulatory strategy experience
• Willingness to travel as needed

Seniority level: Director

Employment type: Full-time

Job function: Research

Industries: Pharmaceutical Manufacturing and Biotechnology Research