Medical Director, Clinical Development — Oncology

Revolution Medicines, Inc.; San Francisco (CA); On-site; USD 295,000 - 339,000; Full time

Job summary

Revolution Medicines is seeking a Medical Director of Clinical Development to lead the clinical development plan for its oncology programs. You will guide trial design, regulatory interactions, and cross-functional collaboration across science, regulatory, and clinical teams.

The role requires MD with oncology focus and 5+ years in clinical development, with leadership capabilities to mentor scientists and coordinate complex studies for potential regulatory submissions.

Qualifications

• MD (oncology training preferred) with 5+ years in clinical development in the pharmaceutical/biotech industry and/or academic/other clinical trial setting; some experience in and understanding of early phase drug development preferred.
• Extensive experience working with the principles and techniques of data analysis, interpretation, and clinical relevance as related to the pharmaceutical/biotech industry.
• Experience in independent generation of trial design, protocol writing/ICF (writing or amendment), constructing appropriate CRF and coordinating cross-functionally.
• In-depth therapeutic area experience/expertise, and relevant clinical trial experience (or clear ability to adapt with transferable skills).
• Strong knowledge of medical aspects of GCP, ICH, FDA, EMA and other relevant guidelines and regulations is required.

Responsibilities

• Lead clinical science and medical aspects of the clinical development strategy and clinical documentation. Represent the clinical development plan on appropriate teams, sub-teams and forums; oversee training of study site personnel, act as primary point-of-contact for questions/enquiries regarding the CDP at a program level, oversee the conduct of medical/safety data reviews and study reporting.
• Potential assignment to complex and high-priority strategic studies for Revolution Medicines' molecules, with expectation to perform responsibilities with independence and clear self-directed leadership.
• Cross-functionally align efforts seamlessly with scientific, regulatory, and commercial objects while executing upon the clinical development plan.
• Lead, mentor, and contribute to a high-performing cross-functional team of clinical development professionals, fostering a culture of collaboration, innovation, and excellence.
• Oversee all aspects of clinical trial design and execution, including site selection, patient recruitment, data management, and regulatory compliance.
• Establish and maintain strong relationships with clinical investigators, regulatory agencies, and key stakeholders.
• Gather, analyze and interpret clinical data, providing strategic insights to inform critical decisions and guide program development.
• Manage clinical development timelines effectively, ensuring efficient resource allocation and achievement of milestones.
• Stay abreast of the latest scientific advancements and regulatory trends in the field of clinical development.
• Potential to manage multiple direct reports.

Skills

MD (oncology training)

Clinical development

Data analysis & interpretation

Trial design & protocol writing

Regulatory knowledge (GCP/ICH/FDA/EMA)

Cross-functional leadership

Investigator engagement

Team mentorship

Education

MD degree in Oncology

Job description

Revolution Medicines is seeking a Medical Director of Clinical Development to lead the clinical development plan for its oncology programs. You will guide trial design, regulatory interactions, and cross-functional collaboration across science, regulatory, and clinical teams.

The role requires MD with oncology focus and 5+ years in clinical development, with leadership capabilities to mentor scientists and coordinate complex studies for potential regulatory submissions.