Medical Director, Clinical Development — Lead Trials

OpenKrill; United States; Hybrid; USD 242,000 - 290,000; Full time

Benefits offered by this job

Health coverage

Wellness stipend

401(k) match

Tuition reimbursement

Commuter benefits

Disability and life insurance

Annual bonus opportunities

Equity grants

Job summary

Kailera Therapeutics, Inc. is seeking an experienced Medical Director, Clinical Development to lead design and execution of clinical programs for our obesity-focused pipeline.

This role requires strong clinical insight, biotech drug development experience, and cross-functional collaboration in a fast-paced environment. The position can be based in our hub in Waltham, MA (onsite 3-4 days/week) or remote with periodic in-person hub visits, offering comprehensive health coverage, wellness support,

Qualifications

• 2+ years of industry experience in clinical development.
• Hands-on experience designing and executing clinical trials.
• Experience with regulatory submissions and global regulatory filings.
• Understanding of GCP, trial design, regulatory requirements, and safety monitoring.
• Excellent written and verbal communication skills, including protocol and regulatory document writing.
• Demonstrated ability to engage with KOLs, investigators, and cross-functional teams.
• Can work independently, self-starter attitude.

Responsibilities

• Medical monitoring and safety activities.
• Provide medical leadership in the design, planning, and execution of clinical development strategies across multiple studies.
• Acts as the medical contact at the company for clinical/medical issues.
• Interprets, reports, and prepares oral and written results of product research, in concert with senior clinical personnel.
• Serve as the medical expert for assigned assets studies.
• Contribute to regulatory interactions and strategy, such as IND/CTA/NDA submissions.
• Collaborate with Clinical Operations on site selection, patient recruitment strategies, and trial execution.
• Oversee and support data interpretation, analysis, and clinical study reports.
• Work closely with Regulatory, Safety, CMC, and Translational Science teams.
• Partner with external collaborators, KOLs, CROs, and investigators.
• Support scientific publications, conference presentations, and other external communications.
• Participate in safety review meetings and provide clinical input into adverse event evaluation and reporting.

Skills

Clinical development

Regulatory knowledge

KOL engagement

Communication

Independent work

Education

MD or equivalent

Job description

Kailera Therapeutics, Inc. is seeking an experienced Medical Director, Clinical Development to lead design and execution of clinical programs for our obesity-focused pipeline.

This role requires strong clinical insight, biotech drug development experience, and cross-functional collaboration in a fast-paced environment. The position can be based in our hub in Waltham, MA (onsite 3-4 days/week) or remote with periodic in-person hub visits, offering comprehensive health coverage, wellness support,