Senior Medical Director, Clinical Development: Lead Trials

Kailera Therapeutics; Massachusetts; On-site; USD 296,000 - 355,000; Full time

Benefits offered by this job

Health coverage

401(k) match

Tuition reimbursement

Wellness stipend

Equity opportunities

Job summary

Kailera Therapeutics is seeking an experienced Senior Medical Director, Clinical Development to drive design and execution of clinical development programs in obesity and related conditions. You will provide medical leadership across multiple studies, act as the medical contact, and contribute to regulatory strategy in a fast-paced biotech environment.

The role requires 4+ years in clinical development, MD or equivalent, and a strong background in trial design, GCP, and cross-functional

Qualifications

• 4+ years of industry experience in clinical development, preferably in a biotech or small pharma environment.
• Hands-on experience designing and executing clinical trials.
• Understanding of GCP, clinical trial design, regulatory requirements, and safety monitoring.
• Excellent written and verbal communication skills, including protocol and regulatory document writing.
• Demonstrated ability to engage with KOLs, investigators, and cross-functional teams.
• Can work independently; self-starter attitude.
• Advanced PowerPoint skills; working knowledge of Excel and other commonly used clinical systems/tools.
• Ability to manage multiple studies and deadlines in a fast-paced environment.
• Must be exceptionally detail oriented.

Responsibilities

• Responsible for medical monitoring/reporting and safety activities.
• Provide strategic medical leadership in the design, planning, and execution of clinical development strategies across multiple studies.
• Acts as the medical contact at the company for clinical/medical issues.
• Interprets, reports, and prepares oral and written results of product research, in concert with senior clinical personnel.
• Serves as the medical expert for assigned assets studies.
• Contribute to regulatory interactions and strategy, including IND/CTA submissions and briefing packages.
• Collaborate and work closely with Clinical Operations to ensure appropriate site selection, patient recruitment strategies, and high-quality trial execution.
• Oversee and support data interpretation, analysis, and clinical study reports.
• Work closely with internal stakeholders, including Regulatory, Safety, CMC, Medical Affairs, and Translational Science teams.
• Drive partnerships with external collaborators, KOLs, CROs, and investigators.
• Support scientific publications, conference presentations, and other external communications.
• Participate in safety review meetings and provide clinical input into adverse event evaluation and reporting.

Skills

Clinical development

GCP knowledge

Trial design

Regulatory writing

KOL engagement

Cross-functional collaboration

Independent worker

PowerPoint

Excel

Multitasking

Education

MD or equivalent

Tools

EDC (Electronic Data Capture)

Regulatory databases

Job description

Kailera Therapeutics is seeking an experienced Senior Medical Director, Clinical Development to drive design and execution of clinical development programs in obesity and related conditions. You will provide medical leadership across multiple studies, act as the medical contact, and contribute to regulatory strategy in a fast-paced biotech environment.

The role requires 4+ years in clinical development, MD or equivalent, and a strong background in trial design, GCP, and cross-functional