Mechanical Engineer

Nanopath; Cambridge (MA); On-site; USD 90,000 - 130,000; Full time

Job summary

Nanopath, based in Cambridge, MA, is seeking a Mechanical Engineer to support the design, development, and testing of its point-of-care molecular diagnostic reader platform.

You will design mechanisms, engage vendors, and ensure manufacturability while upholding ISO 13485 design controls through verification testing in a fast-paced startup setting.

Qualifications

• Degree in Mechanical Engineering with 3+ years of industry experience.
• Experience designing mechanisms and assemblies in regulated environments.
• Familiarity with manufacturing processes (machining, 3D printing, molding).
• Experience ISO 13485 design controls and verification testing.
• Knowledge of fluidics and instrument-cartridge interactions is a plus.
• Strong communication and startup adaptability.

Responsibilities

• Support mechanical design, development, and testing of the POC reader platform.
• Design, source, build, and test mechanical assemblies and interactions with cartridges and chemistry.
• Develop mechanisms for cartridge engagement, fluid actuation, and instrument motion.
• Design, build, and test systems from prototype to verification.
• Collaborate with suppliers and contract manufacturers on parts.
• Coordinate with cross-functional teams to define requirements and ensure integration.
• Execute design controls and maintain ISO 13485 documentation.

Skills

Design controls

GD&T

DFM

Mechanical design

Regulated environment

Communication

Startup adaptability

Education

B.S./M.S. in Mechanical Engineering

Tools

SolidWorks

ASME Y14.5 GD&T

Job description

Nanopath is developing a first-in-class in vitro diagnostics platform to transform how diseases are diagnosed. We aim to replace lengthy molecular testing workflows by bringing rapid, high-quality diagnostics closer to the patient. Our mission is to improve patient outcomes – starting with women – through a purpose-built platform that delivers actionable results within a single office visit.

The company is headquartered at The Engine, the premier tough technology incubator in the Kendall Square ecosystem. We are collectively committed to health equity and the design of solutions for underserved populations and low-resource settings. Corporate sustainability – both environmental and social – is at the forefront of our decision making.

About the Role

• Support the mechanical design, development, and testing of Nanopath's point-of-care molecular diagnostic reader platform.
• Design, source, build, and test mechanical assemblies and mechanisms, including their interactions with the fluidic cartridge and onboard chemistry.
• Develop mechanisms supporting cartridge engagement, fluid actuation, and instrument motion, with attention to reliability and manufacturability.
• Design, build, and test systems from prototype through commercial module verification.
• Support component sourcing and collaborate with vendors and contract manufacturers on custom and off-the-shelf parts.
• Collaborate with cross-functional teams (systems, electrical, software, assay) to define requirements and ensure robust cartridge-to-instrument integration.
• Execute design controls and design verification testing, and maintain documentation in compliance with ISO 13485.

Technical Qualifications

• Experience designing mechanisms and mechanical assemblies, ideally in a regulated environment.
• Proficiency in SolidWorks and application of ASME Y14.5 GD&T standards.
• Familiarity with manufacturing processes relevant to mechanisms and assemblies (machining, 3D printing, injection molding, casting, extrusion) with a focus on design for manufacturability and affordability.
• Experience executing ISO 13485 design controls, including design verification testing of module level designs.
• Understanding of fluidic systems and the mechanical interactions between an instrument and a consumable cartridge is a plus.
• Experience with human factors engineering or industrial design for healthcare settings is a plus.

General Qualifications

• B.S. or M.S. in Mechanical Engineering or related technical discipline with at least 3 years of industry experience.
• Ability to work on-site in Cambridge, MA.
• Excellent communication and presentation skills, highly organized with demonstrated curiosity, scientific rigor and creative problem-solving.
• Proactive self-starter with eagerness to adapt to a fast-paced, dynamic startup environment.
• Passion for technology translation and willingness to shape Nanopath’s future.

Don’t meet every single requirement? Studies have shown that women and people of color are less likely to apply to jobs unless they meet every single qualification. At Nanopath we are dedicated to building a diverse and inclusive workplace, so if you’re excited about this role but your past experience doesn’t align perfectly with every point in the job description, we encourage you to apply anyways. You may be just the right candidate for this or other roles!

Nanopath Inc. is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

Nanopath does not accept unsolicited resumes from recruiters or agencies and we will not be responsible for any fees related to resumes that are unsolicited. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Nanopath, and Nanopath will not owe any referral or other fees with respect thereto.