Mass Spectrometry Scientist, tLNP Analytical Development

BioSpace; North Chicago (IL); On-site; USD 120,000 - 160,000; Full time

Benefits offered by this job

Paid time off

Medical/dental/vision insurance

401(k) plan

Short-term incentive programs

Job summary

AbbVie’s Analytical Development group seeks a Mass Spectrometry SME to advance LC-MS methods for tLNP drug development. You will characterize mRNA, oligonucleotides, lipids, and intact LNPs while supporting cross-functional teams in formulation and process development.

The role requires hands-on LC-MS experience, instrument optimization, and collaborative work with R&D partners to deliver high-quality analytical data and regulatory submissions.

Qualifications

• PhD with 0–3 years of industry experience preferred.
• Experience with LC-MS analyses of mRNA, oligonucleotides, antibodies, and LNP is a strong plus.
• Hands-on LC-MS method development and instrument troubleshooting are required.

Responsibilities

• Operate, maintain, and troubleshoot MS and LC methods for tLNP analytics.

Skills

Mass spectrometry expertise

Analytical method development

Collaboration & cross-functional work

Documentation & ELN proficiency

Independent and team work

Education

Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or closely related field

Tools

Orbitrap

TOF MS

LC-MS instruments

XCalibur

Protein Metrics

FreeStyle

Skyline

BioPharma Finder

MassLynx

Job description

AbbVie’s Analytical Development group seeks a Mass Spectrometry SME to advance LC-MS methods for tLNP drug development. You will characterize mRNA, oligonucleotides, lipids, and intact LNPs while supporting cross-functional teams in formulation and process development.

The role requires hands-on LC-MS experience, instrument optimization, and collaborative work with R&D partners to deliver high-quality analytical data and regulatory submissions.