Manufacturing Technician

AstraZeneca; Philadelphia (Philadelphia County); On-site; USD 42,000 - 62,000; Full time

Job summary

AstraZeneca plc is seeking an aseptic manufacturing operator to join our production team. You will train on 1st shift (6:00am-2:30pm) for up to a year and then move to 2nd shift (2:00pm-10:30pm) with a shift differential.

You will run autoclaves, pumps, and filling lines through Thaw, Blend, Fill, Stage, and Prep. Responsibilities include setting up/breaking down equipment, environmental monitoring, materials handling, and maintaining strict cGXP records while updating SOPs and batch records.

Qualifications

• High school diploma or GED, Biologic Technician Certification, or an Associate Science Degree.
• At least 1 year of related experience.
• Cleanroom training and aseptic operator qualification required.
• Able to lift up to 40 lbs and work in ultra-low temperature spaces with provided gear.
• Follow safety practices and document to cGXP standards.
• Strong written and verbal communication; works well in a team.

Responsibilities

• Operate aseptic filling lines and related equipment (autoclaves, scales, pumps).
• Prepare equipment setup and breakdown; handle materials.
• Perform environmental monitoring and utility sampling.
• Maintain cleanrooms and cGXP batch records; update SOPs as needed.
• Collaborate with Quality, Maintenance and Materials Management.

Skills

Team player

Detail oriented

Safety conscious

Documentation

Education

High school diploma or GED

Biologic Technician Certification

Associate Science Degree

Tools

Microsoft Teams

Excel

Word

PowerPoint

SAP

LIMS

LMS

TrackWise

Job description

The Job in a Nutshell

PLEASE READ CAREFULLY: This position will train on 1st shift Monday-Friday (6:00am-2:30pm) for possibly 1 year and then will permanently be stationed on 2nd shift (Sunday-Thursday (2:00pm-10:30pm). 2nd shift carries a shift differential.

(A rotating OT schedule could be enacted when circumstances warrant, but it's rare.)

You’ll be part of our aseptic manufacturing crew, running equipment like autoclaves, scales, peristaltic pumps, and automated filling lines through Thaw, Blend, Fill, Stage, and Prep. You’ll also get equipment ready (set up/breakdown), handle materials, do environmental monitoring and utility sampling, keep our cleanrooms spotless, and keep solid cGMP records (and help update SOPs and batch records along the way). You’ll work closely with Quality, Maintenance, and Materials Management—it's a real team effort.

What You Need to Bring (The Must-Haves)

• Education: A high school diploma or GED, a Biologic Technician Certification, or an Associate Science Degree—any one of these gets you in the door
• Experience: At least 1 year of related experience.
• Cleanroom-ready: You're up for completing our aseptic operator training and gowning qualification, and you're cool with cleanroom rules (no jewelry, watches, loose-fitting items, or make‑up on the floor)
• Physicality: You can lift and carry up to 40 lbs. on your own now and then, and you're comfortable working in different environments—including ultra‑low temperature spaces (don't worry, we provide the protective gear!)
• Safety first: You follow workplace safety practices, every time
• Detail-oriented: You can complete documentation accurately to cGXP standards
• Team player: You communicate well, both verbally and in writing, and you thrive in a fast‑moving team environment
• Tech‑comfortable: You know your way around Microsoft Teams, Excel, Word, and PowerPoint, and you're open to using digital tools and learning new AI tools that support our lean/digital journey.

Nice‑to‑Haves (Bonus Points!)

• A bachelor's degree
• Aseptic processing experience in the bio/pharmaceutical industry
• Cleanroom experience in food, medical device, or pharmaceutical manufacturing, or aseptic processing/assembly work. Background in environmental monitoring, pharmaceutical warehousing, or pharmaceutical packaging counts too!
• Hands‑on time with systems like SAP, LIMS, LMS, or Trackwise

Date Posted: 29-Oct-2026

Closing Date: 20-Nov-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.