Manufacturing Supervisor – Downstream Bioprocessing (Night Shift)

Elanco; United States; On-site; USD 90,000 - 120,000; Full time

Benefits offered by this job

8-week parental leave

9 Employee Resource Groups

Annual bonus offering

Up to 6% 401K matching

Job summary

Elanco is seeking a Manufacturing Supervisor for Downstream Bioprocessing at the Elwood, KS site. You will lead nightly operations supporting monoclonal antibody production, ensuring safety, quality, and regulatory compliance on the production floor.

Responsibilities include coaching staff, coordinating with cross-functional teams, and driving continuous improvement while meeting production schedules and batch records.

Qualifications

• Education: High school diploma or equivalent.
• 3+ years in a regulated, commercial manufacturing environment.
• Able to wear gowning and PPE in manufacturing areas.

Responsibilities

• Lead and oversee daily downstream bioprocessing operations.
• Coach and develop manufacturing personnel through training and feedback.
• Ensure compliance with USDA, EMA, and cGMP requirements.
• Maintain safe work practices and a culture of quality on the production floor.
• Coordinate with Quality, Engineering, Maintenance, Validation, and Supply Chain.
• Monitor production performance and schedule adherence.
• Lead investigations and CAPA for operational events and issues.
• Drive continuous improvement for efficiency and compliance.

Skills

Team leadership

Manufacturing supervision

Regulatory compliance

Quality mindset

Education

High school diploma or equivalent

Bachelor's degree in biomanufacturing related field

Tools

SAP

OSI PI

VEEVA

Job description

At Elanco (NYSE: ELAN) – it all starts with animals!

As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose – all to Go Beyond for Animals, Customers, Society and Our People.

At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you’ll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.

Making animals’ lives better makes life better – join our team today!

Your Role: Manufacturing Supervisor Night Shift – Downstream Bioprocessing

The Manufacturing Supervisor – Downstream Bioprocessing is responsible for leading manufacturing personnel and daily operations supporting the bulk production of monoclonal antibody (mAb) products at Elanco's Elwood, Kansas manufacturing site. This role oversees production activities across downstream bioprocessing operations, ensuring production targets are achieved while maintaining the highest standards of safety, quality, regulatory compliance, and Good Manufacturing Practices (cGMP). The supervisor also plays a key role in developing team members, driving operational excellence, and fostering a culture of accountability and continuous improvement.

Your Responsibilities:

• Lead and oversee daily manufacturing operations supporting downstream bioprocessing activities, including buffer formulation, cell clarification, protein A chromatography, and Tangential Flow Filtration, while partnering with upstream and fill/finish and ensuring adherence to production schedules.
• Supervise, coach, and develop manufacturing personnel through performance management, training, and regular feedback to build a high-performing, engaged team.
• Ensure manufacturing activities are performed in compliance with USDA, EMA, and cGMP requirements, approved procedures, and batch production records.
• Maintain a strong presence on the production floor to promote safe work practices, operational excellence, and a culture of quality and accountability.
• Coordinate with Quality, Engineering, Maintenance, Validation, Supply Chain, and other cross-functional teams to support compliant and efficient manufacturing operations.
• Monitor production performance, equipment readiness, and schedule adherence while ensuring timely completion of batch records, SAP transactions, and manufacturing documentation.
• Lead or support investigations, root cause analyses, and corrective and preventive actions (CAPA) for operational events, deviations, and equipment or process issues.
• Drive continuous improvement initiatives that enhance manufacturing efficiency, strengthen compliance, and improve overall operational performance.

What You Need to Succeed (minimum qualifications):

• Education : Highschool diploma or equivalent
• Experience : 3+ years experience in a regulated, commercial manufacturing environment.
• Must be able to wear appropriate gowning and personal protective equipment in manufacturing and support areas.

What will give you a competitive edge (preferred qualifications):

• Bachelor’s degree in biomanufacturing related field
• Biomanufacturing experience
• Monoclonal antibody manufacturing
• Understanding of USDA, FDA, EU GMP, cGMP regulatory standards
• Operational excellence, lean manufacturing, six sigma, TPS experience
• Demonstrated success in leadership
• Experience with SAP, OSI PI, VEEVA

Additional Information:

• Travel:minimal 0-5%
• Location: Elwood, KS
• This role is a night shift 5p-5a 12 hour, 2 week rotation. (M,T,F,Sa,Su,W,R)
• Shift structure is subject to change with notice according to business demands
• Premiums available for night and weekend work
• 10% night weekday, 14% night weekend

Elanco Benefits and Perks:

• 8-week parental leave
• 9 Employee Resource Groups
• Annual bonus offering
• Up to 6% 401K matching

Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status

Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job‑related criteria and/or transferrable skills. These tools help ensure a consistent, structured evaluation, but they do not make hiring decisions. All decisions involve a human reviewer. For more information on how we handle personal data, please see our Elanco Workforce Privacy Notice.