Manufacturing Supervisor - Downstream Bioprocessing (Night Shift)

elanco; Elwood (KS); On-site; USD 70,000 - 95,000; Full time

Benefits offered by this job

8-week parental leave

9 Employee Resource Groups

Annual bonus offering

Up to 6% 401K matching

Job summary

Elanco is seeking a Manufacturing Supervisor for Night Shift - Downstream Bioprocessing in Elwood, KS. You will lead daily production, supervise a high-performing team, and ensure compliance with cGMP and regulatory standards to deliver monoclonal antibody products.

The role requires at least a high school diploma and 3+ years in a regulated manufacturing setting; preferred bachelor’s in biomanufacturing. Night shift includes 12-hour rotations with weekend/holiday premiums; travel minimal.

Qualifications

• Education: Highschool diploma or equivalent.
• Experience: 3+ years experience in a regulated, commercial manufacturing environment.
• Must be able to wear appropriate gowning and personal protective equipment in manufacturing and support areas.

Responsibilities

• Lead and oversee daily manufacturing operations supporting downstream bioprocessing activities.
• Supervise, coach, and develop manufacturing personnel through performance management, training, and feedback.
• Ensure manufacturing activities comply with USDA, EMA, and cGMP requirements and batch records.
• Maintain a strong presence on the production floor to promote safe work practices and a culture of quality.

Skills

Leadership

Regulated manufacturing

PPE compliance

SAP

OSI PI

VEEVA

Education

Bachelor's degree in biomanufacturing related field

High school diploma or equivalent

Tools

SAP

OSI PI

VEEVA

Job description

At Elanco (NYSE: ELAN) - it all starts with animals!

As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose - all to Go Beyond for Animals, Customers, Society and Our People.

At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you'll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.

Making animals' lives better makes life better - join our team today!

Manufacturing Supervisor Night Shift - Downstream Bioprocessing

The Manufacturing Supervisor - Downstream Bioprocessing is responsible for leading manufacturing personnel and daily operations supporting the bulk production of monoclonal antibody (mAb) products at Elanco's Elwood, Kansas manufacturing site. This role oversees production activities across downstream bioprocessing operations, ensuring production targets are achieved while maintaining the highest standards of safety, quality, regulatory compliance, and Good Manufacturing Practices (cGMP). The supervisor also plays a key role in developing team members, driving operational excellence, and fostering a culture of accountability and continuous improvement.

Your Responsibilities:

• Lead and oversee daily manufacturing operations supporting downstream bioprocessing activities, including buffer formulation, cell clarification, protein A chromatography, and Tangential Flow Filtration, while partnering with upstream and fill/finish and ensuring adherence to production schedules.
• Supervise, coach, and develop manufacturing personnel through performance management, training, and regular feedback to build a high-performing, engaged team.
• Ensure manufacturing activities are performed in compliance with USDA, EMA, and cGMP requirements, approved procedures, and batch production records.
• Maintain a strong presence on the production floor to promote safe work practices, operational excellence, and a culture of quality and accountability.
• Coordinate with Quality, Engineering, Maintenance, Validation, Supply Chain, and other cross-functional teams to support compliant and efficient manufacturing operations.
• Monitor production performance, equipment readiness, and schedule adherence while ensuring timely completion of batch records, SAP transactions, and manufacturing documentation.
• Lead or support investigations, root cause analyses, and corrective and preventive actions (CAPA) for operational events, deviations, and equipment or process issues.
• Drive continuous improvement initiatives that enhance manufacturing efficiency, strengthen compliance, and improve overall operational performance.

What You Need to Succeed (minimum qualifications):

• Education : Highschool diploma or equivalent
• Experience : 3+ years experience in a regulated, commercial manufacturing environment.
• Must be able to wear appropriate gowning and personal protective equipment in manufacturing and support areas.

What will give you a competitive edge (preferred qualifications):

• Bachelor's degree in biomanufacturing related field
• Biomanufacturing experience
• Monoclonal antibody manufacturing
• Understanding of USDA, FDA, EU GMP, cGMP regulatory standards
• Operational excellence, lean manufacturing, six sigma, TPS experience
• Demonstrated success in leadership
• Experience with SAP, OSI PI, VEEVA

Additional Information:

• Travel: minimal 0-5%
• Location: Elwood, KS
• This role is a night shift 5p-5a 12 hour, 2 week rotation. (M,T,F,Sa,Su,W,R)
• Shift structure is subject to change with notice according to business demands
• Premiums available for night and weekend work
• 10% night weekday, 14% night weekend

Don't meet every single requirement? Studies have shown underrecognized groups are less likely to apply to jobs unless they meet every single qualification. At Elanco we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!

Elanco Benefits and Perks:

• 8-week parental leave
• 9 Employee Resource Groups
• Annual bonus offering
• Up to 6% 401K matching

#LI-HL

Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protec