Manufacturing Associate II / III, Cell Culture (Days)

Biogen, Inc.; Northern (KY); Hybrid; USD 33,000 - 47,000; Full time

Job summary

Biogen is seeking a Manufacturing Associate II/III, Cell Culture at Research Triangle Park, NC to support upstream cell culture operations on a 2-2-3 schedule (days). The role emphasizes bioreactor prep, inoculation, and in-process testing in a cGMP environment.

You will work on days, 6:00 AM–6:00 PM ET, with responsibilities including SOP adherence, accurate documentation, and cross-functional collaboration with MSAT, Quality, and Engineering teams.

Qualifications

• Bachelor’s degree in STEM with 0+ years of direct experience.
• BioWorks Certificate or associate's degree, STEM preferred, 0+ years.
• High School Diploma with at least 0.5 years direct experience.
• Experience in a GxP environment.
• Ability to follow SOPs and work effectively on shift schedules.
• Demonstrated documentation and data integrity skills.
• Knowledge of aseptic technique and cleanroom practices preferred.

Responsibilities

• Prepare bioreactors by executing automated CIP/SIP recipes using DeltaV.
• Perform filtration, centrifugation, and harvest operations.
• Standardize and calibrate pH and DO probes during bioreactor preparation.
• Perform inoculation of bioreactors across multiple scales.
• Support cell growth operations, including media feeds and process additions.
• Conduct routine sampling and in-process testing to monitor product quality.
• Standardize and maintain laboratory and manufacturing equipment, including Vi-Cell Blu/XR, Osmometer, pH meters, RapidPoint BGA, Conductivity meters, biosafety cabinets, small-scale centrifuges.
• Accurately document activities in accordance with cGMP and SOP requirements.
• Maintain a clean, safe, and compliant manufacturing environment.
• Collaborate cross-functionally with Manufacturing, MSAT, Quality, and Engineering teams.

Skills

SOP adherence

Documentation

Problem solving

Team collaboration

Attention to detail

Education

Bachelor’s degree in STEM

BioWorks Certificate

Associate degree in STEM

High School Diploma with experience

Tools

DeltaV

Syncade

pH meters

Centrifuges

Biosafety cabinets

Osmometer

Vi-Cell Blu/XR

Conductivity meters

Job description

## Manufacturing Associate II / III, Cell Culture (Days)Apply: On Campus: Research Triangle Park, NC: Full time: Posted Today: REQ24299**About This Role**Our factories run 24/7 operations. Our manufacturing teams work 12-hour shifts (either Days or Nights) on a 2-2-3 calendar rotation. * **Shift Details:** This role follows a 2-2-3 calendar rotation on days (6:00 AM – 6:00 PM ET)* **Internal Shift Details:** Black Days rotating schedule Our Manufacturing Associates perform processing steps and manufacturing support activities in our Drug Substance facility in Research Triangle Park (RTP). These teams are the backbone of our operations – each playing a critical role in delivering our therapies to the patients who need them. Our teams are organized by the steps in the biomanufacturing process that they operate in; including – Upstream (Cell Culture), Downstream (Purification), and Media & Solution Preparation. Manufacturing Associates perform these critical steps in a clean environment governed by Current Good Manufacturing Practices (cGMP). This role’s primary focus is on Upstream Cell Culture operations. **What You’ll Do** * Prepare bioreactors by executing automated CIP/SIP recipes using DeltaV* Perform filtration, centrifugation, and harvest operations* Standardize and calibrate pH and DO probes during bioreactor preparation* Perform inoculation of bioreactors across multiple scales* Support cell growth operations, including media feeds and process additions* Conduct routine sampling and in-process testing to monitor product quality* Standardize and maintain laboratory and manufacturing equipment, including: + Vi-Cell Blu/XR + Osmometer + pH meters + RapidPoint BGA + Conductivity meters + Biosafety cabinets + Small-scale centrifuges* Accurately document activities in accordance with cGMP and SOP requirements* Maintain a clean, safe, and compliant manufacturing environment* Collaborate cross-functionally with Manufacturing, MSAT, Quality, and Engineering teams **Who You Are**You’re driven by a mission to save lives and bring a deep sense of purpose to the work you do. Biomanufacturing is complex, and you thrive in fast-paced environments where learning agility, problem-solving, and adaptability are essential. **Required Skills for a Manufacturing Associate II:** $23.56 - $30.77 Pay Range* The following combination of academic and/or relevant experience may be considered: + Bachelor’s degree from an accredited college or university, STEM preferred and 0+ years of direct experience + A BioWorks Certificate or associate's degree, STEM preferred and 0+ years of direct experience + A High School Diploma (or equivalent) and at minimum of .5 years of direct experience* Previous experience in a GxP environment* Ability to follow SOPs and work effectively on shift schedules* Demonstrated documentation and data integrity skills* Understanding of aseptic technique and cleanroom practices is preferred **Required Skills for a Manufacturing Associate III:** $25.96 - $34.13 Pay Range* The following combination of academic and/or relevant experience may be considered: + Bachelor’s degree from an accredited college or university, STEM preferred and at minimum .5 years of direct experience + A BioWorks Certificate or associate's degree, STEM preferred and at minimum 1 year of direct experience + A High School Diploma (or equivalent) and at minimum of 1.5 years of direct experience* Previous experience in a cGMP environment* Ability to follow SOPs and work effectively on shift schedules if required* Demonstrated documentation and data integrity skills* Knowledge of aseptic technique and cleanroom practices* Exposure to Delta V, Syncade, or similar systems* Experience performing bioreactor preparation, inoculation, and monitoring is preferred* Hands-on experience with mammalian cell culture operations is preferredJob Level: Entry Level