Manufacturing Associate II, Cell Culture (Days)

Biogen; North Carolina; On-site; USD 32,000 - 42,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

Paid vacation (15 days)

Holiday pay

401(k) matching

Tuition reimbursement

Employee stock purchase plan

Job summary

Biogen in Research Triangle Park is seeking an entry-level Manufacturing Associate II to support upstream cell culture operations in a 2-2-3 schedule. You'll help prepare bioreactors, run filtration and harvest steps, and ensure proper documentation in a cGMP setting.

The role emphasizes aseptic technique, cross-functional collaboration, and adherence to SOPs. Competitive benefits accompany the base pay and shift structure with 12-hour days or nights.

Qualifications

• Bachelor's degree or equivalent in a STEM field with relevant experience.
• BioWorks certificate or an associate's degree with related experience.
• High School diploma with at least 0.5 years direct experience in GMP setting.
• Previous experience in a GxP environment is preferred.
• Ability to follow SOPs and work on rotating shifts.
• Strong documentation and data integrity skills.
• Understanding of aseptic technique and cleanroom practices is preferred.

Responsibilities

• Prepare bioreactors by executing automated CIP/SIP recipes using DeltaV.
• Perform filtration, centrifugation, and harvest operations.
• Calibrate pH and DO probes during bioreactor prep.
• Inoculate bioreactors across multiple scales.
• Support cell growth operations, including media feeds and process additions.
• Conduct routine sampling and in-process testing to monitor product quality.
• Document activities per cGMP and SOP requirements.
• Maintain a clean, safe, and compliant manufacturing environment.
• Collaborate with Manufacturing, MSAT, Quality, and Engineering teams.

Skills

GxP experience

Follow SOPs

Documentation integrity

Aseptic technique

Education

Bachelor's degree STEM

BioWorks certificate/AS degree

High School diploma + experience

Tools

Vi-Cell Blu/XR

Osmometer

pH meters

RapidPoint BGA

Conductivity meters

Biosafety cabinets

Small-scale centrifuges

Job description

About This Role

Our factories run 24/7 operations. Our manufacturing teams work 12-hour shifts (either Days or Nights) on a 2-2-3 calendar rotation.

Shift Details: This role follows a 2-2-3 calendar rotation on days (6:00 AM - 6:00 PM ET)

Internal Shift Details: Black Days rotating schedule

Our Manufacturing Associates perform processing steps and manufacturing support activities in our Drug Substance facility in Research Triangle Park (RTP). These teams are the backbone of our operations - each playing a critical role in delivering our therapies to the patients who need them.

Our teams are organized by the steps in the biomanufacturing process that they operate in; including - Upstream (Cell Culture), Downstream (Purification), and Media & Solution Preparation. Manufacturing Associates perform these critical steps in a clean environment governed by Current Good Manufacturing Practices (cGMP).

This role's primary focus is on Upstream Cell Culture operations .

What You'll Do

• Prepare bioreactors by executing automated CIP/SIP recipes using DeltaV
• Perform filtration, centrifugation, and harvest operations
• Standardize and calibrate pH and DO probes during bioreactor preparation
• Perform inoculation of bioreactors across multiple scales
• Support cell growth operations, including media feeds and process additions
• Conduct routine sampling and in-process testing to monitor product quality
• Standardize and maintain laboratory and manufacturing equipment, including: Vi-Cell Blu/XR
• Osmometer
• pH meters
• RapidPoint BGA
• Conductivity meters
• Biosafety cabinets
• Small-scale centrifuges
• Accurately document activities in accordance with cGMP and SOP requirements
• Maintain a clean, safe, and compliant manufacturing environment
• Collaborate cross-functionally with Manufacturing, MSAT, Quality, and Engineering teams

Who You Are

You're driven by a mission to save lives and bring a deep sense of purpose to the work you do. Biomanufacturing is complex, and you thrive in fast-paced environments where learning agility, problem-solving, and adaptability are essential.

Required Skills for a Manufacturing Associate II: $23.56 - $30.77 Pay Range

• The following combination of academic and/or relevant experience may be considered: Bachelor's degree from an accredited college or university, STEM preferred and 0+ years of direct experience
• A BioWorks Certificate or associate's degree, STEM preferred and 0+ years of direct experience
• A High School Diploma (or equivalent) and at minimum of .5 years of direct experience
• Previous experience in a GxP environment
• Ability to follow SOPs and work effectively on shift schedules
• Demonstrated documentation and data integrity skills
• Understanding of aseptic technique and cleanroom practices is preferred

Job Level: Entry Level

Additional Information

The base compensation range for this role is: $23.56-$30.77

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being ; including, but not limited to:

• Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid‑sized biotechnology company, we provide the stability and resources of a well‑established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life‑changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectiv