Manager of Bioinformatics (Oncology Product Development)

Natera; Oregon; Hybrid; USD 140,000 - 175,000; Full time

Benefits offered by this job

Medical, dental, vision benefits

Life & disability plans

Fertility care benefits

401k benefits

Commuter benefits

Employee referral program

Job summary

Natera is seeking a Bioinformatics Manager to lead a team focused on ctDNA-based diagnostic product development. The role requires guiding computational scientists and collaborating with biostatistics, molecular biology, software engineering and commercial teams through design, validation and launch.

Ideal candidates have a strong bioinformatics/data science background, business acumen, and a track record in leading technical teams and contributing to IP in the diagnostics space.

Qualifications

• Master's degree or Ph.D. in a quantitative discipline (bioinformatics, engineering, applied mathematics, statistics, or similar).
• 4–8 years of post-graduate data science/bioinformatics experience and 1–3 years as technical lead.
• Experience moving algorithm-based products through commercialization in diagnostics or related field.
• 1–2 years of management leading a technical team with proven leadership.

Responsibilities

• Provide technical leadership for product development projects and drive validation and launch.
• Optimize workflows, improve tools, and test analysis pipelines for diagnostic tests.
• Supervise bioinformatics and data science staff and develop their skills.
• Input in experiment design, analysis and interpretation using mathematical principles.
• Work independently and contribute to IP and documentation.

Skills

Python

R

Statistical modeling

Machine learning

NGS data analysis

Mathematics

Communication

Project leadership

Education

Master's or PhD in quantitative field

Job description

Natera is currently seeking a Bioinformatics Manager to join the Bioinformatics team focused on Oncology Product Development. In this role, the individual will manage a team of Bioinformaticians and Data Scientists and provide technical leadership in the design, development and validation of ctDNA-based diagnostic tests. This position requires extensive cross-functional collaboration with biostatistics, molecular biology, software engineering and commercial departments. The ideal candidate will have a strong background in bioinformatics and data science, optimally with experience in the LDT assay development space, and an established record of project and technical leadership.

PRIMARY RESPONSIBILITIES:

• Provide technical leadership for product development projects by representing the bioinformatics team in cross-functional interactions and moving products through the full development process through validation and commercial launch.
• Lead the effort to optimize workflows, improve tools and pressure test analysis pipelines for diagnostic tests, including the detection of cancer-associated variants and the implementation of evidence-based quality control thresholds.
• Supervise bioinformatics scientists and data scientists, managing their technical contributions, prioritizing resources, and taking responsibility for their technical and professional development.
• Provide input on experiment design, analysis and interpretation based on expert understanding of Natera's technology and relevant mathematical principles.
• Work at a high level of independence and responsibilities in carrying out assignments.
• Contribute to our intellectual property portfolio.
• Set standards for rigorous data analysis and lead the production of high-quality documentation.

QUALIFICATIONS:Requirements:

• Master's degree or Ph.D. in a quantitative discipline (bioinformatics, engineering, applied mathematics, statistics, or similar).
• Minimum of 4-8 years of post-graduate experience in a data science and/or bioinformatics role and 1-3 years of experience as technical lead in diagnostics or a related field.
• Experience moving algorithm-based products through commercialization and launch in a medical or biological application such as diagnostic testing, medical imaging, or biotechnology.
• 1-2 years of management experience leading a technical team with demonstrable evidence of leadership and team management skills.

Desirable, but not required:

• Prior experience analyzing cancer-associated variant detection data

KNOWLEDGE, SKILLS, AND ABILITIES:

• Experience using Python or R for scientific data analysis and visualization.
• Strong foundation in statistical modeling/machine learning, including probability theory and estimation/classification methods.
• Experience with analysis of next-generation sequencing data, preferably including algorithm development or optimization.
• Proven ability to apply mathematical principles to solve real estimation problems and implement practical solutions.
• Excellent analytical, problem-solving and decision-making skills to independently make sound judgments and find creative solutions to moderately complex problems.
• Experience leading technical projects, including defining and meeting project milestones, delegating tasks to more junior team members, and ensuring the quality of technical deliverables.
• Excellent communication skills and the desire to work in a dynamic and collaborative environment.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA$140,000—$175,000 USD

OUR OPPORTUNITYNatera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world‑class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

• Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
• Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
• Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
• We also offer a generous employee referral program!

For more information, visitNatera is proud to be an Equal Opportunity Employer.

We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives.

Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.