Manager, Commercial Execution Operations, CNE

Revolution Medicines, Inc.; United States; On-site; USD 144,000 - 216,000; Full time

Job summary

Revolution Medicines, a global oncology company, is establishing its European headquarters in Basel and expanding its CNE region operations. The Manager Commercial Execution Ops CNE Region leads high-complexity, cross-functional initiatives ensuring governance, alignment across Europe, and scalable frameworks for business integration.

The role supports the VP, General Manager CNE Region, building trusted partnerships with leadership teams and global functions in a dynamic, fast-paced environment.

Qualifications

• Bachelor’s degree in Business Administration, Life Sciences, or related field.
• Project management certification required or in progress.
• Experience in project management, business operations, or chief-of-staff roles.
• Proven ability to influence governance and deliver strategic business outcomes.
• Strong event management and stakeholder engagement capabilities.

Responsibilities

• Assist CNE leadership team and stakeholders to execute complex crossfunctional initiatives across CNE operations.
• Support and maintain integrated governance frameworks with country, global and regional priorities.
• Own a fast paced regional calendar, managing strategic meetings across time zones.
• Lead planning and execution of internal CNE events, including annual kick-offs and quarterly cycle meetings.
• Lead organization of monthly CNE Leadership Team meetings and governance meetings, including agenda setting and minutes.

Skills

Cross-functional leadership

Project management

Stakeholder engagement

Organizational skills

Communication skills

Education

Bachelor’s degree in Business Administration, Life Sciences, or related field

Project management certification

Tools

Smartsheet

Asana

Microsoft Office Suite

Job description

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS.Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

Revolution Medicines is establishing its European headquarters and expanding its presence across the CNE (Central, Northern, Eastern Europe) region. TheManager Commercial Execution Ops CNE Region role leads the execution of high-complexity, cross-functional initiatives that ensure operational readiness, governance, and alignment across the European region. Serving as an operational support to the VP, General Manager CNE Region, this individual drives the design and implementation of scalable frameworks that enhance business integration and cross-regional collaboration. The ideal candidate thrives in a dynamic, fast-paced environment, demonstrates strong business acumen, and can build trusted partnerships across leadership teams and global functions.

Key responsibilities include:

• Assist CNE leadership team, cross-functional stakeholders and leaders to execute complex, crossfunctional initiatives across CNE operations.
• Support and maintain integrated governance frameworks and ensure strategic alignment with country, global and regional priorities.
• Own a fast paced regional calendar, managing strategic meetings across time zones.
• Lead planning and execution of internal CNE events, including annual kick-offs and quarterly cycle meetings.
• Lead organization of monthly CNE Leadership Team meetings and CNE governance meetings, including agenda setting, minute taking, follow up tracking and logistics.
• Work in close collaboration with other project coordinators and operational team members in European Commercialization to ensure a connected and engaged team.
• Plan and execute international travel itineraries including flights, ground transport, visas, accommodations, and contingency planning. Ensure seamless transitions between engagements and proactive resolution of travel disruptions.
• Ensure operational excellence, budget tracking, transparent reporting and documentation integrity.
• Lead coordination of internal contract management and purchasing across functions and affiliates, ensuring alignment with Legal, Compliance and Finance governance.
• Support and coordinate office setup activities across CNE and affiliate sites under Finance, Legal, and HR governance.
• Drive ad hoc tasks of various sizes and complexity.
• Build trusted relationships across the organization and externally to faciliatete effective collaboration.
• Handle confidential matters with utmost discretion and professionalism.

Required Skills, Experience and Education:

• Bachelor’s degree in Business Administration, Life Sciences, or related field.
• 8+ years experience with progressive responsibilities leading highly-complex, cross-functional programs within the biopharma or life sciences industry.
• Experience in project management, business operations, or chief-of-staff roles.
• Project management certification required or in progress.
• Proven ability to influence governance and deliver strategic business outcomes across global operations.
• Exceptional organizational skills and ability to manage multiple priorities with precision and speed.
• Strong event management and stakeholder engagement capabilities.
• Strong interpersonal and communication skills with the ability to work effectively across functions and cultures.
• Demonstrated understanding of governance structures and compliance principles in a regulated industry.
• Fluent in English; additional European languages are an asset.
• Must be based in Basel.

Preferred Skills:

• Experience supporting senior executives or leadership teams in a regional or global matrix organization.
• Familiarity with European affiliate operations, business systems, and internal policy frameworks.
• Advanced proficiency in Microsoft Office Suite and project management tools (e.g., Smartsheet, Asana).
• Proactive, solution-oriented mindset and ability to thrive in a start-up or scale-up environment.

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