Manager, Applied AI, Advanced Informatics

Regeneron; Village of Tarrytown (NY); Hybrid; USD 150,500 - 245,500; Full time

Job summary

Regeneron is seeking a Manager, Applied AI to lead research-facing ML work within the Advanced Informatics team. You will design AI/ML solutions for health data, frame problems with clear success criteria, and build reusable analytics capabilities used across informatics.

The role requires 4–6 years of applied AI/ML experience, strong Python and ML stack skills, and familiarity with NLP or multimodal models.

Qualifications

• Bachelor’s degree required; PhD or Master’s strongly preferred.
• 4–6 years of progressive applied AI/ML experience.
• Strong foundations in ML theory and real-world data problems.

Responsibilities

• Design and develop applied AI/ML solutions for health informatics use cases.
• Translate business and clinical informatics challenges into AI/ML problem statements.
• Build and maintain ML pipelines including data ingestion, feature engineering, model training, and evaluation.
• Conduct experiments, benchmarking, and ablation studies to validate model performance.
• Collaborate with clinical informaticists, data engineers, and production AI/ML engineers.
• Stay current with foundation models, LLMs, and health data applications.
• Document research and contribute to internal reports/publications.
• Communicate model behavior and limitations to technical and non-technical stakeholders.

Skills

Supervised learning

Unsupervised learning

Self-supervised learning

Deep neural networks

Python stack

NLP models

Multimodal models

LLM fine-tuning

Experiment tracking

Model versioning

Reproducible research

Cloud ML infra

Independent work

Education

Bachelor’s degree in CS/ML/Data Science

PhD or Master’s preferred

Tools

PyTorch

TensorFlow

HuggingFace Transformers

scikit-learn

pandas

NumPy

MLflow

Weights & Biases

DVC

AWS SageMaker

GCP Vertex AI

Azure ML

Job description

Build a future together

The Manager, Applied AI is a research-facing technical role within the Advanced Informatics team responsible for designing and developing applied AI solutions across health data systems and analytical pipelines. This role works closely with senior applied AI leaders to formulate ML problems against complex health data, validate methods against clinical ground truth, and build reusable analytical capabilities that the broader informatics team depends on.

The ideal candidate brings solid grounding in AI/ML theory, hands‑on experience applying it to real-world data problems, and is excited to deepen their expertise at the intersection of machine learning and health informatics.

When & Where

This can be a remote position in the United States or an on-site position at our Tarrytown, NY; Armonk, NY; or Warren, NJ offices.

Discover Your Role

• Design and develop applied AI/ML solutions for health informatics use cases, from problem framing and data exploration through model development and evaluation.
• Translate business and clinical informatics challenges into well‑scoped AI/ML problem statements with clear success criteria.
• Build and maintain ML pipelines including data ingestion, feature engineering, model training, and evaluation, in close collaboration with production engineering.
• Conduct experiments, benchmarking, and ablation studies to validate model performance and inform modeling decisions.
• Partner with clinical informaticists, data engineers, and production AI/ML engineers to integrate models into informatics workflows.
• Stay current with advances in foundation models, large language models, retrieval‑augmented generation, and their application to biomedical and health data domains.
• Contribute to research documentation, internal technical reports, and where appropriate, external publications or conference presentations.
• Communicate model behavior, limitations, and performance clearly to both technical and non‑technical stakeholders.

This Role Requires

Bachelor's degree (BS) in Computer Science, Machine Learning, Data Science, Biomedical Informatics, Statistics, or a closely related field is required. A Ph.D. or Master’s degree is strongly preferred given the research-facing nature of this role.

Minimum Years of Experience

4–6 years of progressive experience in applied AI/ML, with demonstrated ability to independently develop and evaluate models. Ph.D. graduates with relevant research experience may be considered at the lower end of this range.

Knowledge, Skills & Abilities (Required)

• Solid understanding of supervised, unsupervised, and self‑supervised learning; deep neural networks; and modern ML frameworks (PyTorch, TensorFlow, or equivalent).
• Strong command of Python and the scientific ML stack (scikit‑learn, HuggingFace Transformers, pandas, NumPy, etc.).
• Experience designing and evaluating NLP or multimodal models, including fine‑tuning or prompt engineering with large language models.
• Proficiency with experiment tracking, model versioning, and reproducible research practices (MLflow, W&B, DVC, or similar).
• Familiarity with cloud‑based ML infrastructure (AWS SageMaker, GCP Vertex AI, Azure ML, or equivalent).
• Ability to drive technical work independently and communicate findings clearly across teams.

Knowledge, Skills & Abilities (Preferred)

• Experience with health or life sciences data—EHR/EMR records, claims data, clinical notes, genomic data, or imaging.
• Informatics domain knowledge: familiarity with medical terminologies and ontologies (SNOMED CT, ICD‑10/11, LOINC, RxNorm, OMOP CDM) and machinable health data standards.
• Published work or open‑source contributions in applied ML, NLP, or computational biomedicine.
• Experience with MLOps pipelines, CI/CD for ML, and model observability in production environments.
• Familiarity with federated learning, privacy-preserving ML, or working with data use agreements in regulated environments.

Benefits

Regeneron offers a competitive and comprehensive total rewards package, which may include annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/.

Salary Range (annually)

$150,500.00 - $245,500.00

Equal Employment Opportunity Statement

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.