Executive Director, Responsible AI & Enterprise Governance

Regeneron Pharmaceuticals, Inc.; Village of Tarrytown (NY); On-site; USD 255,000 - 425,000; Full time

Benefits offered by this job

Annual bonuses (potential)

Equity awards

Pension or retirement benefits

401(k) company match

Health and wellness programs

Fitness centers

Insurance benefits (medical, dental, …

Paid time off

Family support benefits

Job summary

Regeneron Pharmaceuticals, Inc (USA) seeks an Executive Director for Responsible AI & Enterprise Governance to shape and run our enterprise AI governance framework. You will partner with Legal, Compliance, and the CISO to ensure safe, compliant AI use and build governance as a catalyst for AI adoption.

You will lead cross-functional teams across model validation, guardrails engineering, and regulatory compliance, driving enterprise-wide AI risk management and GxP validation strategies.

Qualifications

• Bachelor's degree required; advanced degree may be required for certain scientific/clinical positions.
• 17+ years of experience in AI governance, risk management, regulatory affairs, or compliance.

Responsibilities

• Drive the enterprise AI governance program with senior business stakeholders across all Regeneron functions.
• Lead the citizen development governance program with safe, auditable, enterprise-approved boundaries for non-technical builders.
• Define and own Regeneron's enterprise AI governance strategy across all model types, risk tiers, and deployment contexts.
• Build and lead a team of specialists across model validation, guardrails engineering, regulatory compliance, and citizen development governance.
• Establish the enterprise AI risk framework—taxonomy, classification standards, and control requirements across ML, foundation models, LLMs, and agentic systems.
• Set the technical assurance including validation frameworks, red-teaming, production monitoring, and pre-production sign-off gates.
• Own the end-to-end AI model lifecycle governance standard from ideation to deployment and monitoring.
• Drive LLM and agentic AI governance—grounding standards, retrieval integrity, tool use controls, autonomous action limits, and human-in-the-loop enforcement.
• Own GxP AI validation strategy and audit readiness across all regulated environments.
• Lead AI regulatory intelligence (FDA, EMA, EU AI Act) coordinated with Legal and business units to anticipate compliance obligations.
• Partner at executive level with Legal, Compliance, Regulatory Affairs, and CISO on regulatory interpretation and standards.

Skills

AI governance

Regulatory affairs

Risk management

Leadership

Cross-functional collaboration

Education

Bachelor's degree

Job description

Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases.

We're looking for an Executive Director, Responsible AI & Enterprise Governance to join our fast-moving Enterprise Data & AI organization. You'll build and run our enterprise AI governance framework, setting the policies, standards, and controls that let Regeneron move fast with confidence, auditability, and trust. You'll partner closely with Legal, Compliance, and the CISO to keep AI use safe, compliant, and aligned with our values. This role reports to the SVP, Chief AI Officer, and offers the chance to shape governance as an accelerant for AI adoption, not a barrier to it.

When & where: Location: This role is open to any of our Tri-State locations: Sleepy Hollow, NY, Tarrytown, NY, Armonk, NY, Warren, NJ or Cambridge, MA

Discover your role:

• Drive the enterprise AI governance program with senior business stakeholders across all Regeneron functions - AI governance forums, use case intake, and enterprise wide accountability
• Lead the citizen development governance program - safe, auditable, enterprise-approved boundaries for non-technical builders
• Define and own Regeneron's enterprise AI governance strategy across all model types, risk tiers, and deployment contexts
• Build and lead a team of specialists across model validation, guardrails engineering, regulatory compliance, and citizen development governance
• Establish the enterprise AI risk framework - taxonomy, classification standards, and control requirements across classical ML, foundation models, LLMs, fine-tuned models, and agentic systems
• Set the technical assurance that includes validation frameworks, red-teaming, production monitoring, and pre-production sign-off gates
• Own the end-end AI model lifecycle governance standard from ideation to deployment and monitoring
• Drive LLM and agentic AI governance - grounding standards, retrieval integrity, tool use controls, autonomous action limits, and human-in-the-loop enforcement
• Own GxP AI validation strategy and audit readiness across all regulated environments
• Lead AI regulatory intelligence e.g. FDA, EMA, EU AI Act and emerging global frameworks, coordinated with Legal and business units to get ahead of compliance obligations
• Partner at the executive level with Legal, Compliance, Regulatory Affairs, and CISO on regulatory interpretation, risk posture, and technical standards

This role might be for you if you:

• Have led AI governance or technical risk functions in a complex, regulated industry and built the teams that execute them
• Bring technical depth to set strategy and leadership range to hire and hold accountable the experts who implement it
• Understand the distinct risk profiles of predictive, generative, and agentic systems and have governed them in production
• Have driven GxP AI validation strategy in a life sciences or biopharma setting
• Stay ahead of FDA AI/ML guidance, EU AI Act, and emerging frameworks — and convert them into enterprise action
• Operate with credibility at the engineering level and the board level
• See AI governance as a strategic capability that accelerates the business — and build it that way

This role requires:

• A Bachelor's degree in a related field (advanced degree required for certain scientific or clinical positions)
• 17+ years of experience in AI governance, risk management, regulatory affairs, or compliance

Does this sound like you?

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.

Salary Range (annually) $255,000.00 - $424,900.00

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories.

Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• annual bonuses or other incentive plans
• equity awards
• pension or retirement benefits
• 401(k) company match
• health and wellness programs
• fitness centers
• insurance benefits (e.g. medical, dental, vision, life and disability)
• paid time off
• family support benefits

For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Please be advised that at Regeneron, we believe we do our best work when we are together.