LNP Research scientist

JMD Technologies Inc.; Lexington (MA); On-site; USD 45,000 - 62,000; Part time

Job summary

JMD Technologies Inc. is seeking a contract-based scientist to support the development and preclinical evaluation of lipid nanoparticle systems for nucleic acid delivery.

The role focuses on formulation, characterization, stability, and in vitro evaluation in a laboratory setting. Responsibilities include LNP formulation at small to mid-scale, stability studies, ligand conjugation support, mammalian cell culture, and data communication through reports and discussions.

Qualifications

• Master’s degree with ~3 years of relevant experience or PhD with 1–3 years in pharmaceutical sciences or related fields.
• Hands-on experience with LNP formulation and small-/mid-scale microfluidic formulation.
• Experience with analytical techniques such as DLS, fluorescence assays, or chromatography.
• Cell culture experience and in vitro mammalian cell assays.
• Strong data handling, documentation, and ability to work independently under SOPs.

Responsibilities

• Formulate and characterize nucleic acid-loaded LNPs at small to mid-scale via microfluidics.
• Conduct LNP stability studies and optimize critical formulation parameters.
• Support ligand conjugation and advanced analytical characterization.
• Perform mammalian cell culture and in vitro assays (potency, uptake, viability).
• Plan, document, analyze, and present experimental results to the team.

Skills

LNP formulation and characterization

Microfluidic formulation

Analytical techniques

Mammalian cell culture

Documentation and communication

Education

Master’s degree in related field

PhD in related field

Tools

Dynamic light scattering

Fluorescence-based nucleic acid assays

Chromatography

Job description

Employment Type: Contract – 1 Year

Status: Accepting Candidates

About the Role

Support the development and preclinical evaluation of lipid nanoparticle (LNP) systems for nucleic acid delivery. This laboratory-based role focuses on LNP formulation, characterization, stability, and in vitro evaluation.

Key Responsibilities

• Formulate and characterize nucleic acid-loaded LNPs at small to mid-scale using microfluidics, with emphasis on reproducibility, scalability, and product quality.
• Conduct LNP stability studies and evaluate critical formulation parameters to support formulation optimization.
• Support ligand conjugation and advanced analytical characterization of targeted LNP systems.
• Perform mammalian cell culture and in vitro assays, including potency, uptake, and viability assessments.
• Plan, execute, document, analyze, and communicate experimental results through reports, presentations, and team discussions.

Qualifications

• Master’s degree with approximately 3 years of relevant experience, or PhD with 1–3 years of relevant experience, in pharmaceutical sciences, chemical engineering, bioengineering, molecular biology, biochemistry, or a related field.
• Hands-on experience with LNP formulation and characterization, including small- to mid-scale microfluidic formulation.
• Experience with analytical techniques such as dynamic light scattering, fluorescence-based nucleic acid assays, chromatography, or related methods.
• Hands-on experience with mammalian cell culture and cell-based in vitro assays.
• Strong experimental documentation, data analysis, scientific communication, and ability to work independently within laboratory procedures and SOPs.

Compensation:

• $39/hr. on w2
• Final compensation within the posted range will depend on qualifications, experience, and interview results.