Lead Translational Liver MPS Scientist

Pittsburgh Tomorrow

Pittsburgh (Allegheny County)

On-site

USD 90,000 - 130,000

Full time

7 days ago

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Job summary

The University of Pittsburgh Liver MPS Team seeks a PhD-level Research Scientist to lead translational research at the interface of microphysiological systems, systems biology, and precision medicine.

Our NIH- and industry-funded projects combine biomimetic liver MPS with multi-omics analysis and quantitative systems pharmacology to stratify patients and accelerate targeted therapies for liver and metabolic diseases.

Qualifications

Ph.D. in cell biology, biomedical engineering, pharmacology or related field.
Hands-on experience with microphysiological systems (MPS) and diverse MPS assays.
Experience establishing 3D cell culture models including primary cells and iPSC-derived hepatic cells.
Proven ability to lead research projects and disseminate results via publications and talks.
Experience training junior scientists.

Responsibilities

Lead all aspects of MPS research from hypothesis development to data interpretation and dissemination.
Design and perform experiments in multiple 3D liver MPS platforms using patient-derived cells.
Develop omics-based, imaging-based, and biochemical assays to quantify phenotypes and drug responses.
Mentor students and technicians in MPS methods and data analysis.
Collaborate with computational modelers to translate findings into actionable strategies.