Lead Scientist, Continuous Manufacturing

Phlow Corp; Richmond (VA); On-site; USD 120,000 - 150,000; Full time

Job summary

Phlow Corp. seeks a Principal Scientist, Continuous Manufacturing to lead process development and scale-up for drug substances in a collaborative setting. You will advise R&D and operate continuous flow equipment while ensuring safety and regulatory compliance.

You will drive modelling, transfer to production partners, and cross-functional collaboration with Analytical Chemistry, EH&S, Engineering, PM, QA and Regulatory Affairs to deliver robust, cost-effective processes.

Qualifications

• Ph.D. with a minimum 3 years of experience, M.S with a minimum 7 years of experience, or B.S. degree with a minimum 10 years of experience in Chemical Engineering
• Process engineering and API manufacturing experience on multi-kilogram scale.
• Experience installing, operating, and maintaining processing equipment for batch and continuous pharmaceutical processes
• Experience with heat and mass transfer calculations in batch and continuous processes
• Experience with process modelling and computational software (ex., Dynochem, ReactionLab, gPROMS, etc)
• Strong interpersonal and communication skills

Responsibilities

• Provide engineering support to Phlow’s R&D labs to ensure the deliverables to customer’s projects are met on time and on budget.
• Lead engineering efforts for pharmaceutical process development in continuous flow mode
• Independently design, install, and operate continuous processing equipment.
• Perform relevant calculations, modelling, and simulations for scale-up of batch and continuous processes
• Maintain accurate, legible, and complete records of all experiments and observations.
• Author progress reports and present scientific results to team members.
• Exhibit a high level of safety awareness and conduct lab operations in a safe manner.
• Contribute to the timely and accurate preparation of regulatory submissions.
• Participate in the ongoing continuous improvements in manufacturing processes resulting in improving product quality, robustness, and cost.
• Collaborate with Analytical Chemistry, EH&S, Engineering, Project Management, Quality Assurance and Regulatory Affairs to ensure strong working relationships with all partners and Phlow employees.

Skills

Process engineering

API manufacturing

Continuous processing

Equipment installation

Equipment operation

Heat and mass transfer

Process modelling

Dynochem

ReactionLab

gPROMS

Communication skills

Education

Ph.D. in Chemical Engineering

M.S. in Chemical Engineering

B.S. in Chemical Engineering

Job description

Phlow Corp. seeks a Principal Scientist, Continuous Manufacturing to lead process development and scale-up for drug substances in a collaborative setting. You will advise R&D and operate continuous flow equipment while ensuring safety and regulatory compliance.

You will drive modelling, transfer to production partners, and cross-functional collaboration with Analytical Chemistry, EH&S, Engineering, PM, QA and Regulatory Affairs to deliver robust, cost-effective processes.