Lead PK/PD Scientist, Veterinary Medicine

Zoetis; United States; A distancia; USD 114.000 - 185.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Short-term incentive

Long-term incentives

Healthcare benefits from day one

401K with match

Profit sharing

4 weeks vacation

Descripción de la vacante

Zoetis, a global leader in animal health, seeks an enthusiastic colleague to join our Veterinary Medicine Research and Development (VMRD) PK/PD Scientist Team to discover and develop novel therapeutics for veterinary medicine.

The successful candidate will be primarily responsible for designing, conducting, analyzing, and interpreting in vivo PK/PD studies in multiple species in support of projects from early research through late-stage development.

Formación

• Ph.D. in pharmacology, biochemistry, or related field with 4+ years of pharmaceutical development experience (DVM DACVCP or Diplom highly desirable).
• Proven ability to design, analyze and interpret in vivo PK and PK/PD studies; biotherapeutics experience desirable.
• Skilled in PK and PK/PD analysis software such as WinNonlin, Monolix or Watson.
• Excellent verbal & written communication skills.
• Self-starter, able to prioritize work and work efficiently with minimal supervision.
• Working knowledge of bioanalytical methodology.
• Knowledge of ADA assays and assessment of immunogenicity of biotherapeutics is highly desirable.
• Experience in PK/PD modeling and simulation such as PBPK, QSP or population PK modeling using NONMEM, R, or related software is highly desirable.
• Experience interacting with regulatory agencies is highly desirable.
• Experience conducting GLP studies is desirable.

Responsabilidades

• Independently design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
• Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens.
• Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects.
• Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid in translation, measurement of target engagement, and dose regimen predictions.
• Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project.
• Present research results to scientific teams, management, and regulatory agencies.
• Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents.

Conocimientos

In vivo PK/PD

PK/PD modeling

Regulatory collaboration

GLP knowledge

Biotherapeutics experience

Communication skills

Analytical software

Educación

Ph.D. in Pharmacology or related field

DVM DACVCP or Dipl. ECVPT desirable

Herramientas

WinNonlin

Monolix

Watson

NONMEM

R

Descripción del empleo

Zoetis, a global leader in animal health, seeks an enthusiastic colleague to join our Veterinary Medicine Research and Development (VMRD) PK/PD Scientist Team to discover and develop novel therapeutics for veterinary medicine.

The successful candidate will be primarily responsible for designing, conducting, analyzing, and interpreting in vivo PK/PD studies in multiple species in support of projects from early research through late-stage development.