Lead OA Pain & Neurogenomics Scientist

Indiana University; Indianapolis (IN); On-site; USD 90,000 - 120,000; Full time

Job summary

The Sankar Laboratory and the Department of Anatomy, Cell Biology & Physiology at Indiana University School of Medicine seek a highly motivated Research Scientist to lead studies within an NIH-funded project on cell-intrinsic pain in osteoarthritis. You will employ KO mouse models, single-cell RNA sequencing, spatial transcriptomics, and advanced microscopy to map neuron dynamics and signaling.

Ideal candidates have a PhD, MD/PhD, or equivalent and experience in OA, transcriptomics, transgenic

Qualifications

• PhD, MD/PhD or equivalent degree in musculoskeletal biology, neuroscience, immunology, molecular biology, or a related field.
• Experience with OA, musculoskeletal biology, and single-cell transcriptomics.
• Experience with transgenic mouse models and colony management.
• Experience in animal surgery or behavioral phenotyping.
• Experience in molecular signaling, advanced microscopy, and bioinformatics.
• Fluency in English.

Responsibilities

• Lead studies on cell-intrinsic pain mechanisms in OA.
• Use global/conditional knockout mouse models and single-cell RNA sequencing with spatial transcriptomics.
• Apply cutting-edge 3D light-sheet microscopy to map sensory neuron dynamics and inflammation.
• Collaborate across disciplines and mentor junior laboratory members.
• Contribute to manuscripts and grant applications.

Skills

Pain research

Single-cell transcriptomics

Transgenic mouse models

Colony management

Animal surgery

Behavioral phenotyping

Molecular signaling

Advanced microscopy

Bioinformatics

Education

PhD

MD/PhD

Job description

The Sankar Laboratory and the Department of Anatomy, Cell Biology & Physiology at Indiana University School of Medicine seek a highly motivated Research Scientist to lead studies within an NIH-funded project on cell-intrinsic pain in osteoarthritis. You will employ KO mouse models, single-cell RNA sequencing, spatial transcriptomics, and advanced microscopy to map neuron dynamics and signaling.

Ideal candidates have a PhD, MD/PhD, or equivalent and experience in OA, transcriptomics, transgenic