Lead CMC Scientist, Cell & Gene Therapies

BioSpace; Waltham (MA); On-site; USD 179,000 - 212,000; Full time

Job summary

CSL Behring seeks a Principal Scientist, CMC to lead Chemistry, Manufacturing and Controls activities for innovative biologics. This senior role provides expert technical guidance, risk-based recommendations, and cross-functional oversight across Development, Quality, Regulatory CMC, Manufacturing, and external partners.

The ideal candidate has deep CMC expertise, strong background in cell and gene therapy, and experience with technology transfer, stability, and lifecycle management.

Qualifications

• 8+ years of industry experience in CMC or related fields.
• Experience in cell and gene therapy is preferred.
• Experience with external development/manufacturing partners.

Responsibilities

• Provide expert input on CMC strategy across development stages.
• Guide risk-based scientific assessments and decisions.
• Mentor colleagues and promote scientific rigor.

Skills

CMC expertise

Cell & gene therapy

Process development

Cross-functional collaboration

Education

Advanced degree in science/engineering

Bachelor's degree with experience

Tools

AAV viral vectors

Baculovirus expression systems

Insect cell platforms

Oligonucleotides

Nucleic acid therapeutics

Job description

CSL Behring seeks a Principal Scientist, CMC to lead Chemistry, Manufacturing and Controls activities for innovative biologics. This senior role provides expert technical guidance, risk-based recommendations, and cross-functional oversight across Development, Quality, Regulatory CMC, Manufacturing, and external partners.

The ideal candidate has deep CMC expertise, strong background in cell and gene therapy, and experience with technology transfer, stability, and lifecycle management.