Lead Application Engineer

Aprecia Pharmaceuticals, LLC; Mason (OH); On-site; USD 120,000 - 180,000; Full time

Job summary

Aprecia Pharmaceuticals, LLC is seeking a Lead Application Engineer to drive the integration of ERP, SCADA, MES, LIMS, QMS, and CMMS systems in support of our 3D printing pharmaceutical manufacturing platforms. You will design and govern an integrated software architecture that is secure, scalable, and compliant with relevant regulations.

Reporting to cross-functional teams, you will oversee vendor management, implement integration solutions, and develop dashboards for critical manufacturing

Qualifications

• B.S. degree in Computer Science or related field.
• 5–10 years of enterprise application integration experience in life sciences.
• Ignition/Sepasoft experience preferred.
• Strong understanding of Cloud vs on-premise architecture implications.
• Proficient in designing and implementing integration solutions using ESBs, API management platforms, and ETL/ELT tools.
• Hands-on experience with SOAP, REST, XML, JSON, and message queuing.
• Familiarity with security protocols such as authentication, authorization, and data encryption.
• IT hardware or electrical/controls engineering experience or similar cross-disciplinary skillset desirable.

Responsibilities

• Oversee selection and implementation across the full enterprise software architecture.
• Collaborate with engineering, IT, and stakeholders to understand integration requirements.
• Manage vendor relationships, including contracts, timelines, services, and deliverables.
• Ensure secure, compliant systems per cGMP and regulatory guidelines.
• Develop integration solutions using middleware technologies and API management tools.
• Maintain integration workflows, data mappings, and transformation rules.
• Oversee development and maintenance of dashboards highlighting critical manufacturing data.
• Troubleshoot integration issues to ensure high availability and performance.
• Document integration designs, configurations, and maintenance procedures.
• Stay updated with latest integration technologies and best practices.

Skills

Integration architecture

Vendor management

Regulatory compliance

cGMP knowledge

APIs / API management

ETL/ELT tools

SOAP/REST/XML/JSON

Cloud vs on-premise

3D printing domain

Project coordination

Communication

Education

B.S. in Computer Science or related field

Tools

Ignition/Sepasoft

Job description

General Purpose of Position :

The Lead Application Engineer is responsible for developing, overseeing, implementing, and maintaining the integration between various enterprise software applications, such as ERP, SCADA, MES, LIMS, QMS, and CMMS systems. They will work closely with cross-functional teams to develop and execute integration strategies that enable seamless data flow and process automation across the organization in support of Aprecia’s novel 3DP (3D Printing) pharmaceutical manufacturing platforms in a flexible, scalable, and secure architecture.

Primary Duties and Responsibilities (Essential Functions) :

1 Oversee all aspects of the selection and implementation of applications across the full enterprise software architecture typical of a life sciences manufacturing & technology company. 2 Collaborate with engineering teammates, application owners, IT, and business stakeholders to understand integration requirements and align solutions with organizational goals. 3 Manage relationships with external vendors, including the selection, coordination, and oversight of contracts, timelines, services, and deliverables. 4 Utilize strong understanding of cGMP and regulatory statutes and guidelines to ensure a secure, robust, and compliant system of applications and data management. 5 Develop, oversee, and implement integration solutions using enterprise integration patterns, middleware technologies, and API management tools. 6 Develop and maintain integration workflows, data mappings, and transformation rules to ensure data consistency and integrity across connected systems. 7 Oversee the development and maintenance of digital dashboards for key stakeholders highlighting critical manufacturing and process data. 8 Troubleshoot and resolve integration-related issues, ensuring high availability and performance of the integrated systems. 9 Document integration design, configurations, and maintenance procedures to facilitate knowledge sharing and support ongoing operations. 10 Stay up to date with the latest integration technologies, best practices, and industry trends to continuously improve the organization’s integration capabilities.

Reporting to this Position :

No direct reports

Travel :

Position may require periodic travel (0-10%)

Work Shift :

This position typically works days but occasional support may be needed at other times

Knowledge, Skills and Abilities :

• Excellent communication and interpersonal skills, with the ability to effectively collaborate with cross-functional teams.
• Strong problem-solving and critical thinking skills, with the ability to identify and implement innovative solutions.
• Proven experience managing external vendors and overseeing complex projects.
• Working knowledge of pharmaceutical industry and cGMPs
• Ability to learn and adapt to demands in a fast-paced work environment.
• Hands-on experience with 3D printing technologies preferred.
• Fluency in Microsoft Office Products (Word, PowerPoint, Excel, Visio)

Education and Experience :

• B.S. degree in Computer Science, Information Systems, Electrical/Controls Engineering, or a related technical field required.
• 5-10 years of proven experience in enterprise application integration with a focus on SCADA, LIMS, MES, Data Historians/Warehousing, or other applications typical of a Life Sciences Manufacturing environment.
• Hands on experience with Ignition/Sepasoft strongly preferred
• Strong understanding of Cloud vs on-premise solutions and their implications on enterprise architecture.
• Proficient in designing and implementing integration solutions using tools such as ESBs, API management platforms, and ETL/ELT tools.
• Hands-on experience with popular integration technologies, such as SOAP, REST, XML, JSON, and message queuing.
• Familiarity with security protocols and practices, such as authentication, authorization, and data encryption.
• IT hardware experience, electrical and controls engineering experience, or other machine design/development relevant cross disciplinary skillset highly desirable.

Physical Demands and Work Environment :

• Ability to stand for extended periods of time within the operations areas wearing required PPE (personal protection equipment)
• Ability to sit for extended periods of time to document and analyze testing results
• Good manual dexterity to operate computer, general office, and engineering equipment
• Able to clearly document specifications and other engineering needs/results
• Fine motor skills to manage more delicate engineering movements
• Good eyesight to read technical/instructional materials and drawings
• Occasional odd body positions (kneeling, bending, reaching) may be required while working with engineering equipment
• Ability to wear appropriate PPE as required for exposure to pharmaceutical operations (e.g. respirators, over-gowning, gloves, etc.)

GENERAL INFORMATION :

The expectation for all employees is to support the company’s mission, vision, culture and core values while adhering to all company policies. The above information is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. The position may require other duties as assigned and can be changed at any time by the company.

We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, sexual orientation, gender identity, national origin, disability or veteran status.