Lead AI Engineer

Regeneron Pharmaceuticals; Village of Tarrytown (NY); On-site; USD 110,000 - 179,000; Full time

Job summary

Regeneron Pharmaceuticals in Sleepy Hollow, NY, seeks a Lead AI Engineer to architect and deliver enterprise-scale AI capabilities, including intelligent agents, LLM-powered apps, and AI platform services. You will lead engineers, drive cross-functional collaboration, and maintain a strong hands-on Python presence.

You will guide design, adoption of cutting-edge AI techniques, and collaboration with senior stakeholders to accelerate drug discovery and clinical research while ensuring security

Qualifications

• Bachelor’s, Master’s or Ph.D. in Computer Science, Computer Engineering, AI or related field.
• 7–10 years of software and AI engineering experience with at least 3 years in a tech lead role.
• Expert-level Python development and production REST API experience (FastAPI).
• Hands-on with AI agents, MCP servers, and LLM-powered apps using LangChain, LangGraph, Strands, CrewAI.

Responsibilities

• Lead end-to-end design, development, and deployment of enterprise AI apps and LLM systems.
• Design and build AI Agents and autonomous systems with agentic frameworks.
• Develop MCP servers for secure integration between AI agents and data sources.
• Apply advanced LLM techniques (prompting, fine-tuning, RAG) for context-aware apps.
• Architect vector databases and RAG pipelines for semantic search.
• Create RESTful APIs to expose AI capabilities to internal platforms.

Skills

Python development

REST API design

AI engineering

Team leadership

Communication

Education

Bachelor’s/Master’s/Ph.D. in CS/CE/AI

Tools

LangChain

LangGraph

Strands

CrewAI

Milvus DB

OpenAI

Anthropic

AWS Bedrock

SageMaker

Kubernetes

Terraform

CI/CD

FastAPI

EKS

Lambda

S3

Docker

CI/CD pipelines

Job description

Job Title: Lead AI Engineer

Department: Digital Transformation – AI Strategy & Execution

Location: Sleepy Hollow, New York

Employment Type: Full-Time

Experience Required: 7–10 Years

About Regeneron

Regeneron is a leading biotechnology company headquartered in Tarrytown, New York, renowned for its innovative research and development of life-changing therapies. With a strong focus on ophthalmology, oncology, inflammation, cardiovascular diseases, and infectious diseases, Regeneron has brought groundbreaking medicines to market — including EYLEA® and the REGEN-COV™ monoclonal antibody cocktail. Our commitment to scientific excellence, cutting‑edge technology, and patient impact has positioned Regeneron as a global leader in biotechnology.

Position Overview

Regeneron is seeking an experienced Lead AI Engineer to serve as a technical leader within the AI Strategy & Execution organization. In this role, you will architect and deliver enterprise‑scale AI capabilities — spanning intelligent agents, LLM‑powered applications, and AI platform services — that accelerate drug discovery, clinical research, and enterprise productivity. You will lead a team of engineers, drive cross‑functional collaboration, and communicate AI strategy to senior stakeholders, all while maintaining a strong hands‑on presence in Python development and AI systems design.

Key Responsibilities

AI Engineering & Intelligent Systems

• Lead end-to-end design, development, and deployment of enterprise AI applications and LLM‑powered systems, ensuring production‑grade quality, security, and scalability.

• Design and build AI Agents and autonomous systems using agentic frameworks including LangChain, LangGraph, Strands, and CrewAI, applying ReAct, tool‑use, planning, and memory management patterns.

• Develop and operate MCP (Model Context Protocol) servers for standardized, secure integration between AI agents and enterprise data sources.

• Apply advanced LLM techniques — prompt engineering, fine‑tuning, and retrieval‑augmented generation (RAG) — to build intelligent, context‑aware applications.

• Architect and manage vector database solutions (Milvus DB preferred) supporting semantic search, knowledge retrieval, and RAG pipelines.

• Architect RESTful APIs that expose AI capabilities to internal platforms and downstream business applications.

LLM & AI Platform Management

• Administer and continuously evolve the enterprise LLM and AI Gateway platform, including model routing, access controls, rate limiting, usage observability, and multi‑model orchestration.

• Evaluate and onboard new foundation models (OpenAI, Anthropic, AWS Bedrock, and others) in alignment with enterprise security and compliance standards.

Technical Leadership & Team Management

• Lead, mentor, and manage a team of AI engineers, conducting code reviews, setting technical standards, and fostering a culture of engineering excellence.

• Contribute to the organization’s AI roadmap through architectural design reviews, technical strategy, and proof‑of‑concept development.

• Troubleshoot complex issues across AI model serving, APIs, and platform layers.

Cross-Functional Collaboration & Stakeholder Engagement

• Partner with business units, data scientists, and clinical research teams to identify AI opportunities and translate them into scalable technical solutions.

• Serve as the primary technical point of contact for enterprise AI platform discussions, presenting findings and recommendations to senior leadership.

• Engage with external vendors, cloud providers, and AI research organizations to evaluate and integrate emerging capabilities.

Requirements & Qualifications

Education

• Bachelor’s, Master’s, or Ph.D. in Computer Science, Computer Engineering, Artificial Intelligence or a related technical field.

Experience

• 7–10 years of progressive software and AI engineering experience, with at least 3 years in a technical lead or senior individual contributor role.

• Expert‑level Python development skills, including production REST API development with FastAPI.

• Proven hands‑on experience building AI Agents, MCP Servers, and LLM‑powered applications using frameworks such as LangChain, LangGraph, Strands, or CrewAI.

• Hands‑on experience with vector databases (Milvus DB preferred) for RAG and semantic search pipelines.

• Experience administering LLM API gateway platforms, including model routing, observability, access governance, and multi‑model orchestration.

• Experience with foundation models from OpenAI, Anthropic, AWS Bedrock, and other major providers.

• Working knowledge of AWS cloud services relevant to AI workloads (SageMaker, Bedrock, EKS, Lambda, S3); Kubernetes and CI/CD experience is a plus.

• Experience in the biotechnology, pharmaceutical, or healthcare industry preferred.

Technical Competencies

• Programming: Python (expert‑level).

• AI Frameworks & Runtimes: LangChain, LangGraph, Strands, CrewAI; AWS Bedrock AgentCore.

• LLM Techniques: Prompt engineering, fine‑tuning, RAG, vector databases (Milvus DB preferred).

• AI Platform: LLM Gateway management, model routing, multi‑model orchestration, TensorFlow, PyTorch.

• API Development: RESTful API design, FastAPI, OpenAPI/Swagger.

• Cloud & Infrastructure (supporting): AWS (SageMaker, Bedrock, EKS, Lambda, S3), Kubernetes, Docker, Terraform, CI/CD pipelines.

• Data & Analytics: Databricks, Dataiku, Postgres, Redis, NoSQL databases.

• Observability: Monitoring, logging, and distributed tracing for AI workloads.

Certifications

Required:

• AWS Certified Machine Learning – Specialty

Nice to Have:

• AWS Certified Solutions Architect – Professional

• Certified Kubernetes Administrator (CKA)

Soft Skills & Leadership

• Exceptional communication skills with the ability to present AI concepts to both engineering teams and executive stakeholders.

• Proven track record of leading engineering teams and managing delivery across cross‑functional groups.

• Strong problem‑solving mindset with a bias toward pragmatic, production‑ready AI solutions.

• Collaborative and proactive in engaging with business units, compliance, and external partners.

Joining Regeneron as a Lead AI Engineer offers a unique opportunity to shape enterprise AI strategy, build transformative platforms, and make a meaningful impact on the advancement of global healthcare. If you are a driven technical leader with deep expertise in AI systems and a passion for innovation in a regulated environment, we invite you to apply.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$109,900.00 - $179,300.00