Laboratory Technologist III, iPSC & Advanced Cellular Models

The Jackson Laboratory; Farmington (CT); On-site; USD 57,000 - 95,000; Full time

Job summary

The Jackson Laboratory in Farmington, CT is seeking an experienced laboratory professional to advance iPSC workflows, culture, cryopreservation, and differentiation. You will operate and troubleshoot automated systems, maintain records, and ensure quality across batches.

You will write SOPs, train colleagues, collaborate with scientists and engineers, and participate in process improvements. A strong background in mammalian cell culture and data integrity is essential for success in this

Qualifications

• Advanced hands-on proficiency in mammalian cell culture and aseptic technique.
• Direct experience with iPSC culture, cryopreservation and recovery, differentiation, 3D culture, organoids, assembloids.
• Independently execute standardized laboratory workflows and maintain accurate records.
• Experience operating and troubleshooting laboratory automation and high-throughput systems.
• Ability to evaluate process and quality data, recognize deviations, and communicate recommendations.
• Experience writing or revising SOPs and training materials.

Responsibilities

• Perform and monitor developing manual and automated workflows for iPSC expansion, cryopreservation and recovery, differentiation, advanced cellular models, and QC.
• Operate, maintain, and troubleshoot automation, liquid handlers, imaging systems, incubators, and storage equipment; coordinate escalation as needed.
• Review batch, process, and quality data; document issues; propose corrective actions.
• Manage work queues and ensure readiness of materials, reagents, and equipment.
• Execute transferred development protocols and provide feedback on reproducibility and readiness for routine use.
• Write, review, and maintain SOPs, batch records, forms, and training materials.
• Train colleagues, demonstrate techniques, and serve as a technical resource.
• Collaborate with scientists, engineers, quality partners, and operations to troubleshoot and implement improvements.
• Lead or participate in process-improvement, validation, deviation-investigation, and projects.
• Follow safety, aseptic, data integrity, and quality-system requirements.
• Perform other duties as assigned.

Skills

Mammalian cell culture

Aseptic technique

iPSC culture

Laboratory automation

Data review

SOP writing

Education

Associate’s degree in biological sciences

Bachelor’s degree in a relevant field

In lieu of an associate’s degree, two additional years of relevant experience

Job description

Key Responsibilities & Essential Functions

• Perform and monitor developing manual and automated workflows for iPSC expansion, cryopreservation and recovery, differentiation, advanced cellular models, and associated quality-control activities.


• Operate, maintain, and perform advanced troubleshooting on assigned laboratory automation, liquid handlers, imaging systems, cell counters, incubators, cryogenic storage equipment, and other laboratory instrumentation; coordinate service or escalation as needed.


• Review batch, process, and quality data; recognize deviations, adverse trends, or workflow failures; accurately document issues; and recommend corrective or preventive actions within the scope of the role.


• Manage assigned work queues and maintain the readiness of materials, reagents, controls, cell banks, inventories, and equipment needed for safe and efficient execution.


• Execute transferred development protocols and provide structured feedback regarding reproducibility, cycle time, automation compatibility, failure modes, training needs, and readiness for routine use.


• Write, review, and maintain SOPs, work instructions, batch records, forms, logs, training materials, and other controlled operational documents.


• Train and cross‑train colleagues, demonstrate advanced laboratory techniques, assess readiness on assigned procedures, and serve as a technical resource without direct supervisory responsibility.


• Collaborate with scientists, automation and software engineers, quality partners, and operations staff to troubleshoot workflows, evaluate proposed equipment or process changes, and implement approved improvements.


• Lead or participate in process‑improvement, validation, qualification, deviation-investigation, and special projects within assigned areas.


• Follow applicable requirements for laboratory safety, aseptic technique, data integrity, document control, and quality systems.


• Perform other duties as assigned.

Knowledge, Skills & Abilities

• Advanced hands‑on proficiency in mammalian cell culture and aseptic technique.


• Direct experience with iPSC culture, cryopreservation and recovery, differentiation, 3D culture, organoids, assembloids, or related advanced cellular models is preferred.


• Demonstrated ability to independently execute standardized laboratory workflows, operate sophisticated equipment, maintain accurate records, and consistently meet quality and productivity expectations.


• Experience operating and troubleshooting one or more types of laboratory automation, liquid‑handling equipment, high‑throughput cell‑culture systems, imaging platforms, or automated data‑capture systems.


• Ability to evaluate process and quality data, recognize deviations or trends, investigate routine failure modes, and communicate evidence‑based recommendations.


• Experience writing or revising SOPs, work instructions, batch records, logs, or training materials.


• Experience working in a document‑controlled or quality‑system environment is preferred.


• Ability to train and support colleagues, explain technical concepts clearly, coordinate work across teams, and contribute positively in a fast‑paced laboratory environment.


• Strong organizational, documentation, communication, and computer skills.


• Demonstrated commitment to safety, data integrity, reproducibility, continuous improvement, customer needs, and responsible stewardship of resources.

Education

• Associate’s degree in biological sciences, biotechnology, laboratory science, or a closely related field.


• Bachelor’s degree in a relevant field.


• In lieu of an associate’s degree, two additional years of relevant experience will be considered in addition to the experience listed below.

Experience

• 4 years of relevant laboratory experience.


• 6 years of relevant laboratory experience.

Pay Range: The pay range for this position is $56,538-$94,658 and is determined based on an assessment of related work experience, geographic location, and internal equity.

About JAX

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org.

EEO Statement

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Bar Harbor

The Jackson Laboratory’s 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.

Ellsworth

The Charles E. Hewett Center in Ellsworth, Maine, is a state‑of‑the‑art facility that serves researchers world wide. The facility represents the culmination of nine decades of unmatched experience and leadership in breeding and caring for laboratory mice. Ellsworth, Maine, is one of Maine’s fastest growing cities. With a growth rate of nearly 20%, Ellsworth is a bustling year‑round community and acts as a hub for surrounding towns. It is located nearby Acadia National Park and hosts numerous special events, concerts and festivals each year. Residents have access to fabulous shopping, recreation, museums, galleries, and dining at a variety of independent restaurants.

Farmington

JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person’s unique genetic makeup. JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500‑square‑foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state‑of‑the‑art computing facilities and laboratories. In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.

Sacramento

The JAX Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California. Sacramento is less than a two‑hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County. Sacramento is the birthplace of the nation’s Farm to Fork movement, and offers excellent restaurants, gastro‑pubs, wineries, theaters, and museums. Outdoor activities are plentiful: Boating, white water rafting, and riding the scenic bicycle trails are popular. Housing and other costs of living are more affordable in Sacramento and its surrounding suburbs than in most other neighboring areas in the North Bay, making Sacramento one of the hottest housing markets in the country year after year.

Augusta

JAX’s Maine Cancer Genomics Initiative (MCGI) is located in Augusta, Maine, in the Harold Alfond Center for Cancer Care (HACCC), at Maine General Hospital. It began operations in 2016 with three overarching goals: to provide cancer genomic testing for Maine cancer patients; to develop and deliver physician education about clinical genomic cancer diagnostics; and to build a network in Maine of oncology practices conducting studies in genomic medicine.