Laboratory Technician

Tucker Parker Smith Group (TPS Group); South San Francisco (CA); On-site; USD 70,000 - 85,000; Full time

Benefits offered by this job

Equity

Job summary

Tucker Parker Smith Group (TPS Group) is seeking an experienced Lab Technician to join a rapidly growing biotechnology company specializing in DNA and RNA sequencing technologies. This role supports high‑throughput molecular biology operations including sample processing, DNA extraction, purification, PCR, and sequencing library preparation.

The ideal candidate has hands‑on experience in a commercial or production laboratory, strong molecular biology skills, and the ability to work independently

Qualifications

• Bachelor's or master's degree in Biology, Molecular Biology, Biotechnology, Biochemistry, or a related scientific field.
• Minimum of 2 years of hands-on experience in a commercial, production, or high-throughput laboratory environment following completion of a degree.
• Experience with DNA extraction, purification, PCR, and/or DNA sequencing workflows.
• Familiarity with molecular biology laboratory techniques and sample preparation.
• Ability to work independently, troubleshoot technical issues, and manage multiple laboratory tasks.
• Strong attention to detail, organizational skills, and commitment to quality.
• Ability to work onsite during the evening shift (4:00 PM–12:00 AM).
• Authorization to work in the United States without employer sponsorship.

Responsibilities

• Process and prepare high volumes of biological samples for DNA sequencing, supporting approximately 1,000–3,500 samples per shift.
• Perform DNA extraction, purification, PCR, and sequencing library preparation.
• Operate laboratory equipment and automated liquid handling systems.
• Perform sample preparation using 96-well plate workflows and established laboratory protocols.
• Load sequencing libraries onto sequencing instruments and monitor sequencing runs.
• Conduct quality control checks to ensure sample integrity, accuracy, and reliable results.
• Troubleshoot laboratory equipment, failed samples, and workflow issues to maintain productivity.
• Maintain accurate sample tracking and documentation using laboratory information management systems (LIMS).
• Maintain laboratory equipment, reagents, and supplies.
• Collaborate with laboratory operations and technical teams to improve efficiency and laboratory workflows.

Skills

High-throughput lab operations

DNA sequencing knowledge

Independent work

Education

Bachelor's or Master's in Biology / Molecular Biology / Biotechnology / Biochemistry

Tools

Opentrons

Tecan

Hamilton

Job description

Employment Type: Full-Time, Direct Hire

Schedule: Monday–Friday, 4:00 PM–12:00 AM

Work Arrangement: 100% Onsite

Compensation: $70,000–$85,000 annually + equity

Position Overview

We are seeking an experienced Lab Technician to join a rapidly growing biotechnology company specializing in DNA and RNA sequencing technologies. This position supports high-throughput molecular biology laboratory operations, including sample processing, DNA extraction, purification, PCR, and sequencing library preparation.

The ideal candidate will have hands‑on experience in a commercial or production laboratory environment, strong molecular biology skills, and the ability to work independently in a fast‑paced, high-volume setting.

Key Responsibilities

• Process and prepare high volumes of biological samples for DNA sequencing, supporting approximately 1,000–3,500 samples per shift.
• Perform DNA extraction, purification, PCR, and sequencing library preparation.
• Operate laboratory equipment and automated liquid handling systems.
• Perform sample preparation using 96-well plate workflows and established laboratory protocols.
• Load sequencing libraries onto sequencing instruments and monitor sequencing runs.
• Conduct quality control checks to ensure sample integrity, accuracy, and reliable results.
• Troubleshoot laboratory equipment, failed samples, and workflow issues to maintain productivity.
• Maintain accurate sample tracking and documentation using laboratory information management systems (LIMS).
• Maintain laboratory equipment, reagents, and supplies.
• Collaborate with laboratory operations and technical teams to improve efficiency and laboratory workflows.

Required Qualifications

• Bachelor's or master's degree in Biology, Molecular Biology, Biotechnology, Biochemistry, or a related scientific field.
• Minimum of 2 years of hands‑on experience in a commercial, production, or high-throughput laboratory environment following completion of a degree.
• Experience with DNA extraction, purification, PCR, and/or DNA sequencing workflows.
• Familiarity with molecular biology laboratory techniques and sample preparation.
• Ability to work independently, troubleshoot technical issues, and manage multiple laboratory tasks.
• Strong attention to detail, organizational skills, and commitment to quality.
• Ability to work onsite during the evening shift (4:00 PM–12:00 AM).
• Authorization to work in the United States without employer sponsorship.

Preferred Qualifications

• Experience with automated liquid handling systems such as Opentrons, Tecan, or Hamilton.
• Experience with next-generation sequencing (NGS) and sequencing library preparation.
• Familiarity with Oxford Nanopore sequencing technology.
• Experience with high-throughput sample processing and 96-well plate workflows.
• Knowledge of laboratory information management systems (LIMS).
• Previous experience in commercial genomics, molecular diagnostics, biotechnology, or sequencing laboratories.