JUNIOR, ASSISTANT, ASSOCIATE, or FULL SPECIALIST - ULLIAN LAB

University of California - San Francisco; San Francisco (CA); On-site; USD 53,000 - 189,000; Full time

Job summary

An established industry player in the field of neuroscience is seeking a motivated Specialist to join a dynamic research team focused on neurodegeneration. The role involves working with cutting-edge technology to study the role of glia in diseases like ALS and FTD. You will be responsible for maintaining and profiling stem cell-derived cells, conducting functional analyses, and collaborating closely with a dedicated team. This position offers a unique opportunity to contribute to impactful research while developing your skills in a supportive environment. If you're passionate about advancing scientific knowledge and eager to make a difference, this role is perfect for you.

Qualifications

• Experience with human iPSC methodology and generation of dopaminergic neurons.
• Strong research background in neuroscience is preferred.

Responsibilities

• Maintenance, differentiation, and profiling of human pluripotent stem cells.
• Conduct functional analysis of derived cells and assist laboratory research.

Skills

Organizational Skills

Collaborative Skills

Communication Skills

Adaptability

Education

Baccalaureate Degree

Master's Degree

Terminal Degree

Tools

CRISPRi/a Technology

Cell Culture Techniques

Immunofluorescence

Microscopy

Job description

Application Window

Open date: July 19, 2024

Most recent review date: Saturday, Aug 3, 2024 at 11:59pm (Pacific Time)

Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Monday, Jan 19, 2026 at 11:59pm (Pacific Time)

Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

JUNIOR, ASSISTANT, ASSOCIATE, or FULL SPECIALIST - ULLIAN LAB

The Department of Ophthalmology at the University of California, San Francisco, is currently accepting applications for a Junior, Assistant, Associate, or Full Specialist position in the laboratory of Dr. Erik Ullian at the UCSF School of Medicine in San Francisco. The Ullian Lab studies the role of glia in neurodegeneration using 3D human brain organoids. We conduct cross-disciplinary research that employs cutting edge human patient and engineered iPSCs as well as CRISPRi/a technology to model neurodegenerative diseases such as frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). More information regarding the Ullian Lab can be found: https://ullianlab.ucsf.edu/blog.

Under direct supervision, the Specialist will be responsible for maintenance, differentiation, and profiling of human pluripotent stem cell derived astrocytes, neurons, and microglia to discover molecular mechanisms impacting neurodegeneration. In addition, functional analysis of the derived cells will be conducted by measuring maturation markers and using targeted assays. The candidate will also be in charge of assembling the differentiated neurons, astrocytes, and microglia in 3D structures following a protocol developed by the Ullian lab. We will be using patient derived cell lines to model neurodegenerative disorders with a focus on amyotrophic lateral sclerosis and frontotemporal dementia. The successful candidate will assist laboratory research by providing technical assistance, preparing and arranging reagents, ordering and inventory of stocks and maintaining an extensive research database for cell banking. Techniques may include, but are not limited to basic molecular biology, biochemistry, cell culturing, genome editing, cloning, immunofluorescence, immunohistochemistry and microscopy. The Specialist will work under the direct supervision of a postdoctoral fellow and/or a higher-level SRA. There may be opportunities for co-authorship of manuscripts if the incumbent is motivated and exerts extra effort.

Required Qualifications:

• Specialists appointed at the Junior rank must possess (or in the process of obtaining) a baccalaureate degree (or equivalent degree) or at least four years of research experience.


• Specialists appointed at the Assistant rank must possess (or in the process of obtaining) a master's degree (or equivalent degree) or a baccalaureate degree with 3 or more years of research experience.


• Specialists appointed at the Associate rank must possess (or in the process of obtaining) a master's degree (or equivalent degree) or five to ten years of experience in the relevant specialization.


• Specialists appointed at the Full rank must possess (or in the process of obtaining) a terminal degree (or equivalent degree) or ten or more years of experience in the relevant specialization.


• The candidate must have organizational and collaborative skills.


• Must be adaptable, reliable, and willing to learn.


• Excellent communication skills are essential.


• Applicants' materials must list current and/or pending qualifications upon submission.


• Applicant must have all requirements met by time of hire.

Preferred Qualifications:

• Candidates with a terminal degree and strong research background in the neuroscience field.


• Prior experience with human iPSC methodology and generation of dopaminergic neurons and astrocytes strongly preferred.

Interested individuals should send their CV, cover letter, and contact information for three (3) references to https://aprecruit.ucsf.edu/JPF05185.


Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary will be commensurate with the applicants experience and training.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100 - $188,200.

Please direct any questions to [e-mail].

Application Requirements

Document requirements

• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).

  
  

• Cover Letter

  
  

• Statement of Research (Optional)

  
  

• Statement of Teaching (Optional)

  
  

• Statement of Contributions to Diversity - Please see the following page for more details: Contributions to Diversity Statement
  
  (Optional)

  
  

• Misc / Additional (Optional)

  
  

Reference requirements

• 3 required (contact information only)

About UC San Francisco

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

* "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.

* UC Sexual Violence and Sexual Harassment Policy: https://policy.ucop.edu/doc/4000385/SVSH

* UC Anti-Discrimination Policy: https://policy.ucop.edu/doc/1001004/Anti-Discrimination

* APM - 035: Affirmative Action and Nondiscrimination in Employment: https://www.ucop.edu/academic-personnel-programs/_files/apm/apm-035.pdf

Job location

San Francisco, CA