Innovation Postdoc: CNS Oligonucleotide Delivery with Peptides

Novartis Group Companies; San Diego (CA); On-site; USD 58,000 - 107,000; Full time

Job summary

Novartis Group of Companies invites applications for a Postdoctoral Fellowship in biomedical research and drug discovery, based in San Diego. The program emphasizes oligonucleotide delivery with peptides and small ligands, with mentorship and opportunities to work across chemistry, biology, and computational sciences.

The ideal candidate has a PhD in a relevant field and a strong track record in synthetic/medicinal chemistry, drug delivery, and biomolecule conjugation.

Qualifications

• PhD in a relevant scientific discipline completed before start date (PhD conferred in 2026 only).
• Rich experience in synthetic/medicinal chemistry and related fields.
• Demonstrated record of scientific achievement (publications, presentations, patents, etc.).
• Strong commitment to learning, innovation, and professional development.

Responsibilities

• Design & synthesize functional small molecules and bioconjugates for biological evaluation.
• Apply analytical and biophysical methods to evaluate purity, stability, binding, and pharmacological properties.
• Develop ideas to advance drug modality, focusing on CNS delivery.
• Prepare and deliver data-driven presentations to inform decisions.
• Publish findings in high-impact journals.
• Collaborate across interdisciplinary teams and work independently.

Skills

Analytical thinking

Chemical biology

Chemistry

Clinical research

Data analysis

Team collaboration

Machine learning

Mammalian cell culture

Education

PhD in a relevant scientific field

Tools

LC-MS/MS

Chromatography

Mass spectrometry

Bioconjugation chemistry

Job description

Novartis Group of Companies invites applications for a Postdoctoral Fellowship in biomedical research and drug discovery, based in San Diego. The program emphasizes oligonucleotide delivery with peptides and small ligands, with mentorship and opportunities to work across chemistry, biology, and computational sciences.

The ideal candidate has a PhD in a relevant field and a strong track record in synthetic/medicinal chemistry, drug delivery, and biomolecule conjugation.