In Vivo Technical Specialist

Nosis Bio; Alameda (CA); On-site; USD 70,000 - 100,000; Full time

Job summary

Nosis Bio in Alameda, CA is seeking a Technical Specialist / Research Associate to perform in-vivo PK/PD and efficacy studies in animal models. This on-site role supports multiple drug-discovery projects and requires hands-on experience with animal studies and collaboration across biology, chemistry, and translational science teams.

A BS or AS with 3+ years in vivo experience and 1+ year in industry is preferred.

Qualifications

• AS or BS degree with 3+ years in vivo experience and 1+ year in industry.
• Experience performing PK/PD and efficacy studies in animal models.
• Ability to work on-site in Alameda, CA.

Responsibilities

• Perform in-vivo PK/PD and efficacy studies in animal models, including IV and subcutaneous dosing, blood sampling, and tissue collection.
• Adopt new techniques and develop disease models for in-house use.
• Ensure proper animal handling and dosing techniques, following protocols and regulatory standards.
• Collect, organize, and document experimental data and maintain lab records.
• Stock/maintain consumables and reagents for experiments.
• Collaborate with biology, chemistry, and translational science teams to support project goals.

Skills

In vivo pharmacology

PK/PD studies

Animal handling

Data recording

Team collaboration

Education

AS or BS degree in related field

Job description

About Nosis Bio:

Nosis Bio is a well-funded biotech startup exclusively focused on cell-specific delivery of RNA therapeutics. We are an all-scientist team of biologists, chemists, and machine learning experts who believe targeted extrahepatic delivery is the key to making RNA therapies the standard of care for a wide range of chronic diseases. We combine deep expertise in receptor biology, generative AI, and high-throughput in vivo data generation to accelerate the development of RNA therapeutics for new tissues. We are addressing a major unmet need across the industry and actively partner with pharmaceutical companies, research institutions, and biotech companies.

About the Role:

We are seeking a Technical Specialist / Research Associate to conduct in-vivo experiments to evaluate the pharmacokinetic (PK), pharmacodynamic (PD), and efficacious properties of therapeutic candidates. The successful candidate will have hands-on experience with in-vivo animal studies and will work closely with multidisciplinary teams to support various drug discovery projects. This is an on-site, in person position.

Responsibilities

• Perform in-vivo PK/PD and efficacy studies in animal models, including intravenous (IV) and subcutaneous dose administration, blood sampling, tissue collection, and necropsy.

• Adopt new techniques and develop disease models for in house use.

• Ensure proper animal handling and dosing techniques, following established protocols and ethical guidelines.

• Collect, organize, and document experimental data accurately and maintain laboratory records in compliance with company protocols and regulatory standards.

• Stock/maintain consumables and reagents necessary for experiments.

• Collaborate with cross-functional teams, including biology, chemistry, and translational science, to support project goals and timelines.

What we’re looking for:

• Ability to work on site in our lab spaces located in the California Bay Area – Research park at Marina Village (Alameda, CA)

• Motivated and proactive with strong problem-solving skills.

• Team-oriented and open to collaboration across scientific disciplines.

• Title and track is dependent on academic and professional experience – we recruit diverse backgrounds including those with academic, non-profit, and industry experiences!

• General Requirement: AS or BS degree with 3+ years in vivo experience (industry or academia) and 1+ years experience in an industry (or similar) environment