In Vivo Research Technician

Science; Alameda (CA); On-site; USD 34,440 - 55,104; Full time

Job summary

Science, an early stage company in California, is seeking an in vivo research associate to perform hands-on wet lab work, including injections, surgeries, and behavior analyses. You will contribute to experiments, data collection, and meticulous documentation in a collaborative team.

Ideal candidates have experience with intravitreal injections, rodent surgeries, and tissue processing; strong communication and organizational skills are essential, with equity and benefits accompanying a base

Qualifications

• Proficiency with IVT injections and intracranial rodent surgeries.
• Proficiency with rodent behavioral assays and tissue processing.
• Ability to follow SOPs with detailed documentation of work.
• Excellent cross-functional communication and collaboration.
• Passionate about rigorous science and teamwork.

Responsibilities

• Perform intravitreal injections to express ambient-light sensitive opsins in the mouse retina.
• Perform intracranial injections.
• Assist with more complex surgeries and workflows.
• Run animal behavior experiments to assess visual and motor function.
• Transcardial perfusions, dissections, and tissue processing.

Skills

IVT injections

Intracranial rodent surgeries

Rodent behavioral assays

Perfusions and tissue processing

SOP documentation

Collaborative science

Cross-functional communication

Respectful work environment

Tools

Retinal histology

Brain histology

Survival rodent surgeries

Molecular techniques (PCR etc)

Mammalian cell handling

Cryobank retrieval

Job description

Science is an early stage company developing technologies for a range of serious unmet medical needs. We take difficult technical risks, confident that with a clear understanding of the problem and strong modern tools, more progress is possible than might be obvious at first. Regardless of role or team, the two factors we weigh most are evidence of exceptional ability and the addition of positive energy to the group. In an early stage, action‑first environment, the ability to independently orient yourself to the problems that need solving and then follow through is essential.

Science is developing biohybrid brain‑computer interfaces and ambient‑light sensitive optogenetic proteins for vision restoration. We are looking for an in vivo research associate passionate about pushing forward these projects. Candidates can look forward to becoming a key contributor in a talented, driven, and interdisciplinary team. Ideal candidates will have extensive experience performing in vivo mouse work, including dosing, intravitreal injections, mouse behavior, stereotaxic surgery, perfusions and tissue dissection and processing. This is a hands‑on wet lab role, with the expectation that you will spend most of your time directly performing experiments. The ideal candidate must possess excellent communication, organizational and prioritization skills.

Role Responsibilities

• Perform intravitreal injections to express ambient‑light sensitive opsins in the mouse retina.
• Perform intracranial injections.
• Assist with more complex surgeries and workflows.
• Perform SQ and IM injections with test articles.
• Run animal behavior experiments to assess visual and motor function.
• Transcardial perfusions, dissections, and tissue processing.

Key Qualifications

• Proficiency with intravitreal (IVT) injections.
• Proficiency with intracranial rodent survival surgeries.
• Proficiency with rodent behavioral assays.
• Proficiency with perfusions and post‑hoc dissection and tissue collection.
• Ability to rigorously follow standard operating procedures, including detailed documentation of your work, to ensure consistent work.
• Thrives when working collaboratively and is passionate about doing rigorous science.
• Excellent cross‑functional communication skills.
• Commitment to helping foster a respectful and supportive work environment.

Preferred Qualifications

• Proficiency with retinal and brain histology.
• Proficiency level with survival rodent surgeries.
• Experience with molecular techniques like nuclear isolation and PCR.
• Experience in mammalian cell handling and cryobank retrieval with strong aseptic technique.

Salary/Pay Range

For individuals hired to work in California, Science is required by law to include a reasonable estimate of the compensation range for this role. We determine your level based on your interview performance and make an offer based on geo‑located salary bands. The base salary range for this full‑time position is $25–$40 per hour + equity + benefits. Within the range, individual pay is determined by work location and additional factors, including job‑related skills, experience, and relevant education or training. Please keep in mind that the equity portion of the offer is not included in these numbers.

Benefits

• Competitive salary and equity
• Medical, dental, vision and life insurance
• Flexible vacation and company‑paid holidays
• Healthy meals and snacks provided for non‑remote employees
• Paid parental, jury duty, bereavement, family care and medical leave
• Dependent Care Flexible Spending Account, subsidized by Science
• Flexible Spending Account
• 401(k)

Science Corporation is an equal opportunity employer. We strive to create a supportive and inclusive workplace where contributions are valued and celebrated, and our employees thrive by being themselves and are inspired to do their best work.

We seek applicants of all backgrounds and identities, across race, color, ethnicity, national origin or ancestry, citizenship, religion, sex, sexual orientation, gender identity or expression, veteran status, marital status, pregnancy or parental status, or disability. Applicants will not be discriminated against based on these or other protected categories or social identities. Science will also consider for employment qualified applicants with criminal histories in a manner consistent with applicable federal, state and local laws.