In Vivo Oncology Scientist I/II (CDX/PDX)

Novartis; Cambridge (MA); On-site; USD 67,000 - 151,000; Full time

Benefits offered by this job

Health benefits

401(k) with company match

Paid time off

Job summary

Novartis' NIBR Oncology in Cambridge, MA is seeking a lab-based in vivo scientist to advance early-stage cancer therapies. The role focuses on executing anti-tumor efficacy and PK/PD studies in CDX, PDX, and syngeneic models, with most time spent in the lab handling animals and collecting data.

Collaboration across multidisciplinary teams is essential. Applicants should have a BS/MS in biological sciences with relevant experience and be proficient in molecular techniques (PCR/ELISA/Western blot)

Qualifications

• BS/MS in Biological sciences with relevant research experience 2+ years (Scientist I) or 4+ years (Scientist II).
• Experience with CDX/PDX xenograft and/or syngeneic models.
• Experience with cell culture and animal handling.

Responsibilities

• Execute in vivo pre-clinical studies to explore hypotheses and establish proof-of-concept.
• Develop CDX/PDX and syngeneic models to evaluate anti-tumor activity and PK/PD.
• Analyze data and present results within a multidisciplinary team.
• Maintain proper documentation and adhere to animal protocols.

Skills

CDX/PDX models

Syngeneic models

Animal handling

Dosing (IV/IP/PO)

Tumor measurements

Flow cytometry

PCR/ELISA/Western blot

Education

BS/MS in Biological Sciences

Tools

Cell culture

PCR

ELISA

Western blot

Flow cytometry

Job description

Novartis' NIBR Oncology in Cambridge, MA is seeking a lab-based in vivo scientist to advance early-stage cancer therapies. The role focuses on executing anti-tumor efficacy and PK/PD studies in CDX, PDX, and syngeneic models, with most time spent in the lab handling animals and collecting data.

Collaboration across multidisciplinary teams is essential. Applicants should have a BS/MS in biological sciences with relevant experience and be proficient in molecular techniques (PCR/ELISA/Western blot)