Immunology Discovery Scientist I

Avalon BioVentures, Inc.; San Diego (CA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Dental insurance

Employee assistance program

Flexible spending account

Parental leave

Relocation assistance (if eligible)

Year-end shutdown

Job summary

Avalon BioVentures, based in La Jolla, California, seeks a Scientist I (Ph.D. or equivalent) to lead functional assay development and screening of therapeutic proteins for immune-mediated diseases.

You will collaborate with protein sciences, analytics, and immunology teams to enable lead discovery and optimize novel therapeutics. Reporting to senior scientists, you will translate biology plans into optimized workflows, mentor junior staff, and maintain rigorous records in a fast-paced biotech

Qualifications

• PhD in cell/molecular biology or immunology, or equivalent with 0–2 years experience.
• Experience in cell-based assay development and optimization.
• Hands-on multi-color flow cytometry for immune cell phenotyping.
• Immunoassays (ELISA, MSD, Luminex) experience.
• Western blot experience.
• Data analysis proficiency (Excel, GraphPad Prism, FlowJo).
• Ability to thrive in a fast-paced matrix environment.

Responsibilities

• Conceptualize, develop and optimize cell-based functional assays to support target validation and screening.
• Order and qualify target reagents and critical consumables.
• Generate benchmark pharmacology and reproducibility datasets.
• Lead day-to-day assay troubleshooting and protocol transfer.
• Independently run functional screening and generate ranking datasets.
• Analyze results, interpret data and propose follow-up experiments.
• Maintain meticulous ELN records.
• Mentor junior team members in routine execution and data practices.

Skills

Cell-based assays

Flow cytometry

Immunoassays

Western blot

Data analysis

Cross-functional work

Education

PhD in cell or molecular biology or immunology

Master’s degree in related field

Bachelor’s degree in related field

Tools

Excel

GraphPad Prism

FlowJo

Luminex

ELISA

Job description

Avalon BioVentures, based in La Jolla, California, seeks a Scientist I (Ph.D. or equivalent) to lead functional assay development and screening of therapeutic proteins for immune-mediated diseases.

You will collaborate with protein sciences, analytics, and immunology teams to enable lead discovery and optimize novel therapeutics. Reporting to senior scientists, you will translate biology plans into optimized workflows, mentor junior staff, and maintain rigorous records in a fast-paced biotech