HR Manager

TRIANA Biomedicines; Lexington (MA); On-site; USD 95,000 - 140,000; Full time

Job summary

TRIANA Biomedicines is seeking an HR Manager who thrives on ownership and impact. You will own core HR systems, processes, and relationships to keep hiring running smoothly and ensure a positive employee experience as we grow.

Working closely with the Director of HR, you’ll take operational ownership of recruiting, payroll, benefits, leave administration, EOR coordination, onboarding, and culture initiatives. If you’re a systems thinker who loves people, this role is designed for you.

Qualifications

• Candidates with 5+ years of progressive HR experience.
• Bachelor’s degree required.
• Familiarity with HRIS/payroll platforms (Paylocity is a plus).

Responsibilities

• Coordinate end-to-end Recruiting Operations with managers, recruiters, and candidates.
• Oversee Payroll & Benefits administration in partnership with Finance.
• Manage PFML leave administration, eligibility tracking, payroll coordination, and reporting.
• Serve as the primary liaison with the Employer of Record provider.
• Own onboarding experience from systems setup to day-one support.
• Drive Employee Experience & Culture initiatives and participate in the Culture Alliance.
• Maintain HR documentation and ensure day-to-day employee needs are met; ensure legal/compliance.

Skills

Systems thinker

Employee advocate

Detail-oriented

Growth-minded

Anticipate needs

HRIS/payroll experience

Education

Bachelor’s degree

Tools

Paylocity

Job description

About TRIANA Biomedicines

TRIANA Biomedicines is a Greater Boston biotechnology company building the leading molecular glue discovery platform to regulate disease targets that are difficult to address with any other modality. TRIANA’s drug discovery engine is powered by high-resolution structural insights, state-of-the-art AI and computational tools, and bespoke chemical libraries. TRIANA’s target-first and rational approach to molecular glue discovery is currently focused on inducing or enhancing the degradation of high-profile cancer targets. The therapeutic approach pioneered by TRIANA has the potential to fundamentally change the paradigm of small molecule drug discovery and bring significant therapeutic benefits to patients. TRIANA is a private company with a top-tier investor syndicate.

The Role

We're looking for an HR Manager who thrives on ownership, impact, and making things better. This role sits at the center of our HR function, responsible for the systems, processes, and relationships that keep hiring running smoothly, employees supported, and our company compliant as we grow.

You’ll work closely with our Director of HR, taking full operational ownership of core HR functions. If you’re someone who improves processes before anyone asks and takes pride in a great employee experience, this role was designed with you in mind.

What You’ll Do

Recruiting Operations

• Coordinate the end-to-end recruiting process across hiring managers, external recruiters, and candidates
• Manage recruiting workflows, systems, and job postings to keep the pipeline running efficiently

Payroll & Benefits Administration

• Prepare, audit, and process payroll in partnership with Finance
• Administer health benefits enrollment and renewals

Leave Administration

• Administer Paid Family and Medical Leave (PFML), including eligibility tracking, payroll coordination, and compliance reporting

Employer of Record (EOR) Coordination

• Serve as the primary liaison with our EOR provider, supporting the full employee lifecycle and ensuring smooth cross-functional coordination

Onboarding

• Own the onboarding experience end to end — systems setup, checklists, and ensuring every new hire feels supported from day one

Employee Experience & Culture

• Execute engagement initiatives, coordinate surveys, and serve as a key employee touchpoint
• Participate as a member of the Culture Alliance

HR Operations & Compliance

• Maintain employee documentation and records, and support day-to-day employee needs
• Ensure operational compliance with applicable employment laws, regulations, and company policies

Vendor Management

• Serve as the day-to-day contact for HR vendors, managing issue resolution, reporting requirements, and timeline coordination

Who You Are

• Systems thinker - you don't stop at completing tasks, you ask how to make the system better
• Employee advocate - you take pride in every hire's experience and every employee interaction
• Detail-oriented - you own accuracy in payroll, compliance, and documentation without reminders
• Growth-oriented - you're eager to develop and take on more over time
• Anticipate needs - you proactively reduce load on others by anticipating needs before they arise
• Experience - you have at least 5 years of progressive HR experience, a Bachelor’s degree, and you are well-versed with HRIS/payroll platforms (Paylocity is a plus)

Room to Grow

This role is designed with your development in mind. As you build expertise, you'll have the opportunity to take on greater ownership, advise managers directly, and grow toward a senior HR role. We're invested in your trajectory — not just your output.

We welcome applications from skilled individuals whose qualifications may not fit the criteria outlined above.

Our Culture

Our Team is our greatest asset at TRIANA. We are proud to work with an integrated group of individuals from an extensive range of backgrounds and experiences. Diversity, Equity, Inclusion and Belonging are important aspects of our culture. We embrace our differences and cultivate an environment that drives better collaboration and innovation by striving to ensure that all coworkers have an ongoing positive experience while being their authentic selves.

Our Values

At TRIANA we are empowered to act. We dare to create transformative medicines for patients. Our creativity and dedication are the glue that unites us in pursuit of our mission.

Thank you for your interest in TRIANA!