Henrich Lab - Junior, Assistant, Associate, or Full Specialist

Uc-SAN-Francisco-Academi; San Francisco (CA); On-site; USD 57,000 - 202,000; Full time

Job summary

UCSF Department of Physical Therapy and Rehabilitation Science invites applications for a Junior/Assistant/Associate/Full Specialist to support translational virology and immunology research. You will process samples, design flow cytometry assays, and mentor trainees while aiding manuscript preparation and community reporting of findings.

The role involves managing lab data and equipment, developing new viral-host panels, and contributing to high-quality, reproducible results for studies

Qualifications

• Baccalaureate degree or equivalent with 4+ years of research experience.
• Master’s degree or a BA/BS with 3+ years of research experience.
• Ten or more years in a relevant specialization for senior levels.

Responsibilities

• Support day-to-day sample processing for human blood and tissue samples.
• Design and execute high-parameter flow cytometry assays for studies.
• Train new users in flow cytometry and viral-host assays.
• Manage daily operation of laboratory equipment and troubleshoot issues.
• Isolate primary immune cells for downstream assays and analyses.
• Mentor students and SRAs on panels and protocols.
• Provide data analysis, manuscript preparation, and scientific communication.
• Assist with project design, implementation, and interpretation.
• Work with HIV and other chronic infections including SARS-CoV-2.
• Participate in PI project development and documentation.

Skills

Cellular immunology

Molecular biology

T cells

Flow cytometry

RNA assay

Grant applications

Manuscript preparation

Education

Baccalaureate degree

Master’s degree

Research experience

terminal degree

Tools

Flow cytometer

RT-qPCR

Multiplexed assays

Data analysis software

Job description

The general responsibilities for this position are to support the Henrich translational virology/immunology lab with day-to-day sample processing (mainly human blood and tissue samples), and testing using specific platforms for viral and viral-host response testing. They will be involved in the intellectual design of novel research directions and strategies. They will also help with manuscript preparation and communication of scientific findings with the larger scientific community.

The position will require to have working experience with the following assays and pathogens:

• (1) Work with teams to design and execute high-parameter flow cytometry assays for in vivo, pre-clinical and translational studies.
• (2) Train and educate new users in the best practices for performing flow cytometry experiments and other viral-host response assays.
• (3) Manage daily operation of various laboratory equipment, including flow cytometry, antibody/antigen quantification platforms, and immunodeficiency.
• (4) Troubleshoot equipment issues, and ensure compliance with safety, quality, and operational procedures.
• (5) Use specialized skills in high-dimensional flow cytometry, cell sorting and multiplexed RT-qPCR.
• (6) Isolate primary immune cells from blood and tissue for downstream phenotypic and functional assays.
• (7) Train and mentor graduate students and SRAs on panel design and best practices for various laboratory protocols.
• (8) Provide ongoing technical guidance to ensure accurate, reproducible, and high-quality research results.
• (9) Work with HIV and other chronic viral infection assays and pathogenesis research (including SARS-CoV-2).
• (10) Provide hand on training on multi-parameter flow cytometry and flow sorting and help with PI project design, implementation and interpretation.

Further, this position will require you to assist with the management of the data and equipment, assist with new viral-host response panel development projects, data analysis using flow cytometry analysis software, maintain current knowledge of best practices for flow cytometry, and provide training for use on the platforms. This position will further require you to mentor and train junior staff members in the laboratory and serve on Division committees.

Required qualifications:

• Junior Specialist - Baccalaureate degree (or equivalent degree) or at least four years of research experience.
• Assistant Specialist - Master’s degree or a baccalaureate degree with at least 3 or more years of research experience.
• Associate Specialist - Master’s degree (or equivalent degree) or at least five to ten years of experience in the relevant specialization.
• Full Specialist - terminal degree (or equivalent degree) or at least ten or more years of experience in the relevant specialization.

Preferred qualifications:

• Knowledge and research experience in cellular immunology and/or molecular biology of viral infections and T cells.
• Basic RNA assay work (e.g. RNA preparation).
• Experience in flow cytometry and/or spatial multiomic analyses.
• Assisting manuscripts and reports.
• Assisting grant applications.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $57,000-$201,700.

• Junior Specialist - Baccalaureate degree (or equivalent degree) or at least four years of research experience.
• Assistant Specialist - Master’s degree or a baccalaureate degree with at least 3 or more years of research experience.
• Associate Specialist - Master’s degree (or equivalent degree) or at least five to ten years of experience in the relevant specialization.
• Full Specialist - terminal degree (or equivalent degree) or at least ten or more years of experience in the relevant specialization.