RESEARCH ASSISTANT II - Chanda Lab

Scripps Research; San Diego (CA); On-site; USD 70,000 - 80,000; Full time

Benefits offered by this job

On-site parking

Comprehensive benefits

Job summary

The Chanda Lab at Scripps Research is seeking a highly motivated Research Assistant II to support antiviral drug and immune modulator discovery programs. You will work in a team to execute high-throughput assays, develop new in vitro assays, and maintain virus stocks and cell culture lines.

Responsibilities include cell culture, assay development for BSL2 viruses, in vivo infection studies, data analysis, and potential guidance to department. Excellent communication skills are essential.

Qualifications

• Requires a bachelor’s degree in biology, biochemistry, microbiology, or related field.
• Requires 3-5 years’ experience. Candidates possessing a master’s degree, 2+ years’ experience required.
• Experience in working with viruses: stock generation, determining infectious titers, setting up in vitro antiviral assays are preferred.
• Experience with cell-based and biochemical assays using methods such as high-content imaging, luminescence, fluorescence, and absorbance are required.
• Experience with database interface and data analysis using Excel and Prism is preferred.

Responsibilities

• Perform human primary cell and cell line culture, preparation of media and reagents.
• Develop in vitro assays for BSL2-level viruses to enable drug discovery flowcharts.
• Conduct in vivo studies of viral infection to evaluate lead compounds.
• Execute high-throughput assays against for screening campaigns
• Data analysis and lab notebook documentation.
• Work under minimal supervision. Independently conducts a wide variety of standard laboratory techniques/procedures while using judgement when necessary to adapt standard methods and techniques.

Skills

Cell culture

High-throughput assays

Data analysis

Lab techniques

Viral handling

Oral and written communication

Education

Bachelor's degree in biology/related field

Master's degree with 2+ years experience

Tools

Excel

Prism

Automated liquid handling

RT-qPCR

NextGen sequencing

Job description

About Us
Calibr-Skaggs Institute for Innovative Medicines was founded on the principle that the creation of new medicines can be accelerated by pairing world‑class biomedical research with state‑of‑the‑art drug discovery and development capabilities. Calibr‑Skaggs is a division of Scripps Research, a first‑of‑its‑kind, nonprofit translational research institute dedicated to creating the next generation of medicines. Scripps Research is ranked the most influential institution in the world for its impact on innovation. Our educational and training programs mold talented and committed students and postdocs into leading‑edge scientists. Leveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr‑Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while reinvesting in further innovative research. We expand basic knowledge in the biosciences and use these fundamental advancements to develop profound innovations that improve wellbeing. Calibr‑Skaggs’ drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected tropical diseases, as well as age‑related and degenerative diseases. If you have a passion for making a difference, this could be your opportunity to join our transformative team.

About Us
Calibr‑Skaggs Institute for Innovative Medicines was founded on the principle that the creation of new medicines can be accelerated by pairing world‑class biomedical research with state‑of‑the‑art drug discovery and development capabilities. Calibr‑Skaggs is a division of Scripps Research, a first‑of‑its‑kind, nonprofit translational research institute dedicated to creating the next generation of medicines. Scripps Research is ranked the most influential institution in the world for its impact on innovation. Our educational and training programs mold talented and committed students and postdocs into leading‑edge scientists. Leveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr‑Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while reinvesting in further innovative research. We expand basic knowledge in the biosciences and use these fundamental advancements to develop profound innovations that improve wellbeing. Calibr‑Skaggs’ drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected tropical diseases, as well as age‑related and degenerative diseases. If you have a passion for making a difference, this could be your opportunity to join our transformative team.
POSITION TITLE: Research Assistant II
Position Summary
The Chanda Lab is seeking a highly motivated individual to support antiviral drug and immune modulator discovery programs. Under this role, the ideal candidate will work in a team environment to support the execution of key high-throughput assays, develop new in vitro assays, and maintain virus stocks and cell culture lines.Resposibilities And Duties

• Perform human primary cell and cell line culture, preparation of media and reagents.
• Develop in vitro assays for BSL2-level viruses to enable drug discovery flowcharts.
• Conduct in vivo studies of viral infection to evaluate lead compounds.
• Execute high-throughput assays against for screening campaigns
• Data analysis and lab notebook documentation.
• Work under minimal supervision. Independently conducts a wide variety of standard laboratory techniques/procedures while using judgement when necessary to adapt standard methods and techniques. Receive instructions on specific assignment objectives, complex features, and possible solutions.
• Provide interpretation and analyses of results. Troubleshoot and modify procedures.
• Responsible for compound handling and plate inventory.
• May assist in designing experiments to complete a segment of overall research plan.
• May provide routine equipment maintenance.
• May provide guidance/training to department.
  

Requirements

• Requires a bachelor’s degree in biology, biochemistry, microbiology, or related field a relevant scientific discipline.
• Requires 3-5 years’ experience. Candidates possessing a master’s degree, 2+ years’ experience required.
• Experience in working with viruses: stock generation, determining infectious titers, setting up in vitro antiviral assays are preferred.
• Experience with cell-based and biochemical assays using methods such as high-content imaging, luminescence, fluorescence, and absorbance are required.
• Experience with database interface and data analysis using Excel and Prism is preferred.
• Experience with automated liquid handling instruments is a plus.
• Experience with gene expression analysis (RT-qPCR, NextGen sequencing, etc.) is a plus.
• Excellent oral and written communications skills
• Troubleshooting capability and flexibility to adapt to a fast-paced environment.
  

Additional Information

• Visa sponsorship is not available for this position.
• Letter of recommendation and/or at least one professional reference is required.
  

Physical Requirments

• This position works in a laboratory or vivarium environment.
• The position requires great attention to detail, dexterity of the hands.
• Details of established essential functions for this position will be addressed/discussed during the interview process.
  

COMPENSATION: The expected hiring range for this position is $70,304 to $79,500 per year, commensurate with experience. Consideration will be given to experience that exceeds the listed requirements.Comprehensive Benefits Include

• Employer Contributed Retirement Plan – Depending on eligibility, employees receive an employer contributed retirement plan (no employee contribution required) and the option to contribute to a 403(b) (which is similar to a 401(k) using your own pre or post‑tax dollars)
• Full Suite of Health and Welfare plans including three medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more
• Access to Flexible Spending Accounts (Medical/Dependent Care)
• Competitive vacation and sick leave policies
• Free, on‑site parking
  

The above statements describe the level of work performed and expected in general terms. The statements are not intended to list all the responsibilities, duties and/or skills required of employees so classified, and the content herein is subject to change due to the business needs of Scripps Research, with or without notice. Furthermore, nothing in this job description shall be interpreted to be in conflict with or to eliminate or modify in any way the employment‑at‑will status of Scripps Research staff.
EEO Statement
The Scripps Research Institute is an Equal Opportunity Employer. We promote diversity of thought, culture, and background in the fields of science. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.