Head of Project Toxicology

Evotec; United States; Remote; USD 180,000 - 320,000; Full time

Job summary

Evotec seeks a VP, Head of Project Toxicology to define and lead the safety assessment strategy across its drug discovery and development portfolio. You will steer safety strategy from early concept through regulatory submission, interfacing discovery and development safety and building a high‑performing toxicology team.

The role offers flexibility with global site options and requires cross‑functional leadership to deliver forward‑looking safety strategies and successful IND/CTA submissions.

Qualifications

• Senior-level toxicology leadership experience in biotech/pharma/CRO
• Strong track record in guiding regulatory toxicology studies and IND/CTA submissions
• Excellent cross-functional leadership and communication skills

Responsibilities

• Define and lead the safety assessment strategy across Evotec program portfolio
• Mentor and develop a high-performing toxicology team
• Guide safety strategy from Target Safety Assessment to Development Candidate nomination
• Serve as SME to support safety design and interpretation for regulatory submissions
• Build global client relationships and ensure alignment on safety strategy

Job description

Remote - Toulouse, Occitanie, France Verona, Veneto, Italy Alderley Edge, England, United Kingdom Vale of White Horse, England, United Kingdom San Francisco, California, United States

Mar 17, 2026

Purpose of the role

As the VP, Head of Project Toxicology, you will define and lead the safety assessment strategy across Evotec drug discovery and development portfolio, ensuring robust, science‑driven decision‑making from early concept through regulatory submission. Serving as the key interface between discovery and development safety, you will shape the direction of our programs, strengthen strategic partnerships, and foster high‑impact collaboration across diverse modalities and therapeutic areas. You will lead and develop a high‑performing team of toxicology experts while working closely with senior leaders across the organisation and our global partners to deliver integrated, forward‑looking safety strategies. This role may be based at any of our global sites, with flexible working arrangements available.

• Own and advance the organisation’s safety strategy for both internal programs and external partnerships, ensuring Evotec’s toxicology framework remains innovative, data-driven, and scientifically robust.
• Inspire, mentor, and develop a team of expert toxicologists , providing strong scientific leadership, strategic direction, and a culture of continual learning.
• Provide pivotal support to Discovery teams across small‑and large‑molecule programs, expertly guiding safety strategy from Target Safety Assessment through Development Candidate (DC) nomination.
• Serve as a trusted subject matter expert to Discovery and Development teams, enabling effective design, execution, and interpretation of regulatory toxicology studies in support of Phase 1 clinical trials and beyond.
• Build and maintain collaborative, trusted relationships with global clients , aligning on safety strategy and ensuring seamless, shared progress toward program objectives.
• Work closely with colleagues across internal functions to foster strong integration, transparent communication, and cohesive decision‑making across the portfolio.
• Model and cultivate a culture of ownership, trust, accountability, and empowerment across the team and broader organisation.

We are an equal opportunities employer and welcome applications from all suitably qualified persons regardless of their race, sex, disability, religion/belief, sexual orientation, or age.

Capability, Knowledge and Experience:

• Extensive senior‑level experience in Toxicology, gained within biotech, pharma, and/or CRO environments, with a strong understanding of the strategic and operational demands of project‑driven organisations.
• Demonstrated leadership of interdisciplinary, cross‑functional teams, with the ability to influence, motivate, and align diverse scientific and operational groups within a complex matrix setting.
• Exceptional communication and scientific synthesis skills, capable of integrating complex data to deliver clear, actionable, and risk‑balanced recommendations to project teams, partners, and senior leadership.
• Proven track record of advancing programs from preclinical discovery into clinical development, across multiple modalities and therapeutic areas.
• Deep expertise in preclinical drug discovery models, with the ability to synthesise complex scientific strategies, navigate uncertainty, and align preclinical plans with development objectives.
• Highly skilled in managing challenging stakeholder dynamics, resolving conflict, and ensuring effective collaboration across discovery, clinical, regulatory, and operational functions.
• Demonstrated experience in preparing and contributing to successful IND/CTA submissions for both small‑molecule and biologic programs.
• Comprehensive knowledge of global regulatory safety guidelines, and their practical application across different modalities and therapeutic landscapes.
• Strong organisational and planning capabilities, with meticulous attention to detail and effective time‑management skills in a fast‑paced environment.
• Creative, strategic problem‑solver with a growth mindset, demonstrating adaptability, curiosity, and an openness to new approaches and emerging science.

Education and Qualifications:

• BSc, MSc, or PhD in Toxicology, Pharmacology, Biology, or a related scientific discipline, with substantial relevant experience.
• DBAT, ERT, UKRT or equivalent professional certification is desirable
• ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.

Evotec

Designing and applying innovative technologies to dramatically expand global access to biotherapeutics.

Just - Evotec Biologics is a pioneering platform that utilizes AI and advanced biomanufacturing to accelerate the development of innovative biotherapeutics from discovery to commercialization.

Biotechnology Research Research Services Professional Services

Company size 501-1,000 employees

Company type Public company Founded 2014

Total funding 0

Momentum

Team growth

Momentum

3% in 12 mo

631 employees on LinkedIn

Mar 23 Apr 26

Capital

Funding history

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