Head of Portfolio Operations - Strategic Programs

MilliporeSigma; Bedford (MA); On-site; USD 158,000 - 267,000; Full time

Job summary

Join a leading bioprocessing company as the Head of Portfolio Operations - Strategic Programs. In this senior leadership role, you will drive strategic initiatives, oversee operational excellence, and lead a high-performing team to meet business objectives. The position requires strong leadership, communication, and strategic skills, with a focus on managing complex, cross-functional initiatives. The ideal candidate will have significant experience in operations and supply chain management within the biotech or pharma industries.

Benefits

Medical Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

401(k) Matching

Paid Time Off

Holidays

Potential Incentive Bonuses

Qualifications

• 8-10+ years’ experience in strategic operations, supply chain, or product management.
• Proven leadership managing senior professionals for at least 5 years.

Responsibilities

• Shape and drive the SUIPS long-range plan to anticipate market trends.
• Lead critical initiatives including Strategic Investment Programs and operational efficiency programs.
• Drive risk mitigation initiatives and ensure seamless integration of functions.

Skills

Leadership

Communication

Negotiation

Stakeholder Management

Strategic Thinking

Education

Bachelor’s or Master’s in Business

MBA

Job description

Head of Portfolio Operations - Strategic Programs

Join us as the Head of Portfolio Operations - Strategic Programs at MilliporeSigma.

Work Your Magic with us! Start your next chapter and join MilliporeSigma.

At Single-Use and Integrated Platform Solutions within Process Solutions, we are committed to transforming the future of bioprocessing. We are seeking a senior leader to join our leadership team as the Head of Portfolio Operations – Strategic Programs for the SUIPS business.

Your Impact:

In this highly visible role, you will act as the strategic engine behind our operational readiness, ensuring competitiveness, resilience, and alignment with market needs through long-range planning, cross-functional execution, and business transformation initiatives. You will serve as a key interface between commercial, supply chain, and operations—translating strategic intent into action.

Your Role:

Strategic & Business Leadership

• Shape and drive the SUIPS long-range plan to anticipate future market trends and business needs.
• Represent SUIPS as IBM business lead, aligning operational priorities with strategic direction.
• Translate commercial and customer needs into operational requirements and execution plans.
• Serve as the main interface to the value chain, ensuring seamless integration of commercial, supply, and quality functions.

Operational Execution & Excellence

• Lead critical initiatives including Strategic Investment Programs (SIPs), operational efficiency programs, and change projects.
• Oversee business case development, CAPA implementations, and investment planning.
• Ensure flawless introduction of new products into operations and supply chains.

Risk Management & Process Optimization

• Drive risk mitigation initiatives, second sourcing strategies, and supply continuity plans.
• Proactively respond to disruptions, compliance risks, and emerging challenges.

Leadership & Team Development

• Lead and inspire a team of senior professionals, fostering a high-performance, accountable, and collaborative culture.
• Drive clarity, focus, and development across the team to meet SUIPS’ strategic objectives.

Minimum Qualifications:

• Bachelor’s or Master’s in Business, Natural Sciences, Engineering, or related disciplines (e.g., Chemistry, Biochemistry, Pharma); MBA is a plus.
• 8-10+ years’ experience in strategic operations, supply chain, product management, strategic marketing, or management consulting.
• Proven leadership managing senior professionals and developing high-performing teams for at least 5 years.
• Experience managing complex, cross-functional initiatives in a matrix environment.
• Strong business acumen, strategic and process-oriented mindset.
• Excellent stakeholder management, communication, and negotiation skills.
• Experience with senior management communication, presentations, and interactions.
• Strong financial skills, capable of translating strategies into business cases and plans.
• Experience with investment planning, CAPA, and operational excellence programs.
• Fluency in English.

Preferred Qualifications:

• Industry experience in biotech, pharma, or life sciences.
• Project management certification is a plus.
• German language skills are a plus.

This role is ideally located in Bedford, Burlington, or Danvers, MA.

Our salary ranges are based on industry data and consider factors such as location, skills, experience, and career level. Benefits include medical, dental, vision insurance, life insurance, disability insurance, 401(k) matching, paid time off, holidays, and potential incentive bonuses.

Pay range: $158,200 - $266,500.

Join us to be part of a diverse, innovative team committed to science and technology, fostering inclusion and belonging. Apply now to help us Spark Discovery and Elevate Humanity!