Head of Platform Technologies MSAT Recombinant Mammalian Drug Substance CoE

BioSpace; Framingham (MA); Hybrid; USD 250,000 - 350,000; Full time

Benefits offered by this job

Health benefits

14+ weeks parental leave

Job summary

Sanofi in Framingham, MA seeks a Head of Platform Technologies, MSAT Recombinant Mammalian CoE to lead an expert team driving next-generation platform technologies, including perfusion culture and continuous purification. You will partner with R&D, Manufacturing and external partners to advance platform innovations and enable the commercial program readiness.

The role requires extensive biopharmaceutical experience, leadership across cross-functional teams, and strong scientific and

Qualifications

• PhD in Chemical/Biological/Sciences/Engineering preferred.
• Master's degree required.
• 10+ years in biopharmaceutical industry.
• 5+ years in biologics drug substance development or manufacturing support.
• Strong leadership and cross-functional collaboration skills.
• Fluency in English (oral and written).

Responsibilities

• Lead evaluation of next-generation platform technologies (perfusion culture, continuous purification, PAT, smart manufacturing).
• Establish and maintain innovation labs within the COE and drive lab digitization and automation.
• Manage external partnerships to support process development and tech transfer.
• Drive MSAT innovation initiatives across platforms and represent scientific excellence externally.
• Provide SME input and guidance for lab work, lifecycle management, and technology transfers.
• Mentor team members and plan workforce development within the CoE.

Skills

Oral and written English fluency

Leadership

Project management

Bioprocess knowledge

Education

PhD in Chemical/Biological/Sciences/Engineering

Master's degree

Job description

Job Title

Head of Platform Technologies, MSAT Recombinant Mammalian Drug Substance CoE

Location

Framingham, MA

About The Job

Sanofi Global MSAT (Manufacturing Sciences, Analytics, and Technology) acts as a crucial link between our R&D and Manufacturing facilities, playing a vital role in securing the present portfolio and delivering future launches of high-quality and innovative drugs and vaccines. By driving its own transformation, Global MSAT fulfils an important function by providing day-to-day Manufacturing Support, focusing on technical and process aspects, effective Life Cycle Management, process robustness enhancement, and yield improvement to optimize performance.

Join our global network and contribute to the launch of 3 to 5 new products annually across various modalities, enabling us to reach and serve more patients and communities. Collaborate with a team of talented and passionate international experts, scientists, and project leaders who are dedicated to inventing, designing, and implementing cutting-edge industrial chemical and biological processes, analytical methods, and process modelling, all in support of Sanofis best-in-class ambition.

The Head of Platform Technologies will lead a dynamic team of Subject Matter Experts within the MSAT Recombinant Mammalian Center of Excellence (CoE), located at Sanofis Massachusetts Framingham Bio-Campus. This team is responsible for establishing stateoftheart innovation laboratory infrastructures and enabling nextgeneration platform technologies, including perfusion cell culture and continuous purification processes.

This senior leadership role will support implementation strategies for commercial programs by collaborating closely with R&D, Manufacturing, and external partners. The team will also spearhead global MSAT innovation initiatives across platforms in partnership with other MSAT groups, while representing MSATs scientific leadership and excellence in both internal and external forums.

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

About Sanofi

Were an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve lives.

Hybrid Schedule

• Hybrid Schedule - 3 days per week onsite- required. *

Main Responsibilities

• Lead the evaluation of Sanofis nextgeneration platform technologies including perfusion cell culture, continuous purification, advanced Process Analytical Technology (PAT), smart manufacturing, and emerging novel process chemistries. Develop the MSAT position on development data package requirements, atscale operational readiness, transferability, labscale model expectations, and MSAT training and expertise needs. Ensure alignment of platformtechnology initiatives with broader organizational objectives such as 2ndgeneration program development, process robustness, and yield improvement.
• Establish and maintain cuttingedge innovation laboratory infrastructures within the COE. Partner with upstream, downstream, and analytical teams to advance lab digitization and automation. Build additional laboratory and pilotscale capabilities that embody Sanofis smartlab future concept.
• Build and maintain strategic relationships with external partners and vendors. Oversee multiple collaboration projects with external suppliers to support manufacturing investigations, process development, raw material characterization, novel equipment and capability assessment, and codevelopment of new technologies. Coordinate these activities seamlessly with MSAT, R&D, and Global Procurement functions.
• Drive global MSAT innovation initiatives in collaboration with other technology platforms (Vaccines, Drug Product, Microbial). Promote knowledge sharing and bestpractice adoption across teams. Represent MSATs scientific excellence in internal forums (smart factory, digital transformation, eco-design, efficiency) and external forums (Bio-Industry forums, biomanufacturing conferences). Strengthening Sanofis reputation as a leader in biopharmaceutical manufacturing innovation.
• Contribute to CoE activities by providing SME input and technical guidance for laboratory work, commercial program life cycle management, and technology transfers. Collaborate effectively with both local and network cross-function teams (e.g. lab, manufacturing, quality, regulatory, business etc.) as needed.
• Mentor and develop team members, fostering their professional growth and technical expertise, while ensuring a diverse technical background and comprehensive skillset coverage for drug substance processes as part of CoE strategic workforce planning.

About You

Basic Qualifications

• PhD degree in Chemical/Biological/ Sciences/Engineering - preferred. Master's degree - required.
• 10+ years of experience related to biopharmaceutical industry - required.
• 5+ years of hands-on experience in biologics drug substance process development, technology development or manufacturing support - required.
• Demonstrated experience leading bioprocess and biomanufacturing innovation initiatives from concept through implementation. Deep knowledge of bioprocess development and operations (e.g., upstream, downstream, drugsubstance stability). Familiarity with laboratory, pilotscale, and largescale manufacturing operations.
• Process knowledge across multiple modalities (e.g. mAbs, small protein and peptide, bioconjugates, nucleotides, Gene/cell therapy, organic chemistry etc.)
• Prior experience of managing suppliers, contractor manufacturing or contract research partners
• Excellent scientific background and effective communication skills. Demonstrated ability to manage and prioritize multiple projects and consistently meet deadlines. Highly motivated individual, with the ability to work independently as well as within cross-functional and cross-site teams
• Oral and written fluency in English

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention andwellness programs and at least 14 weeks gender-neutral parental leave.
• Shape the future of medicine and vaccine delivery with cutting-edge technology, ensuring seamless launches and a resilient global supply.
• Power industry-leading performance by leveraging digital, data, and AI-driven innovation at speed and scale
• Transform lives worldwide by delivering life-changing treatments anywhere, anytime.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmpay Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.