Head of Kidney Forecasting & Analytics

Vertex Pharmaceuticals Inc (US); Boston (MA); On-site; USD 192,000 - 288,000; Full time

Job summary

Vertex Pharmaceuticals in Boston is seeking a Director of Kidney forecasting to build and evolve forecasting capabilities across assets and disease areas. You will lead model development, refine logic, and ensure analyses inform strategy.

As a senior partner to Marketing, Finance, Market Access, Medical and other stakeholders, you will translate data into actionable insights, drive scenario planning, and support portfolio decisions with speed and rigor.

Qualifications

• Bachelor’s degree in a relevant discipline required; advanced degree preferred.
• Minimum 10 years of experience in biotech/pharmaceuticals in a quantitative role; or equivalent consulting experience.
• Significant experience supporting forecasting and analytics for complex assets, portfolios, or multiple disease areas.
• Demonstrated experience working with senior leadership to support commercial planning, financial forecasting, and strategic decision-making.
• Experience in kidney disease or adjacent therapeutic areas preferred.

Responsibilities

• Lead the design, development, refinement, and ongoing evolution of forecasting models across Vertex’s Kidney portfolio, including current and emerging programs.
• Support long-range planning, scenario planning, and near-term operational forecasting across multiple disease areas and business questions.
• Own and enhance forecast frameworks, model logic, core assumptions, analog selections, data inputs, and output structures to ensure models remain decision-useful and adaptable.
• Translate clinical developments, market events, competitive intelligence, access considerations, epidemiology, and other key inputs into robust forecast assumptions and scenarios.
• Deliver high-quality forecast outputs with clear articulation of key drivers, sensitivities, risks, opportunities, and uncertainties.
• Serve as a key forecasting partner to Marketing and other senior cross-functional stakeholders, providing objective perspective, strategic insight, and forecasting rigor.
• Synthesize large, complex, and evolving data sets into clear, actionable recommendations for senior leadership.
• Maintain a strong understanding of the evolving kidney market, including treatment dynamics, patient flow, competitive shifts, and the broader landscape in which Vertex’s assets will compete.
• Support analyses that characterize market opportunity, demand evolution, treatment patterns, and movement of patients across existing and emerging therapies.
• Ensure key performance indicators can be clearly derived from forecast models and used to explain and track forecasted performance.
• Build forecast structures that enable transparent performance drivers, clear interpretation of outputs, and effective scenario assessment.
• Leverage relevant internal and external data sources to support forecasting assumptions and ensure alignment with broader portfolio data and analytics needs.

Skills

Forecasting methodologies

Analytical thinking

Commercial acumen

Stakeholder management

AI tooling familiarity

Communication skills

Education

Bachelor's degree

Advanced degree preferred

Tools

Snowflake

SQL

Power BI

Python

SAS

VBA

Job description

Vertex Pharmaceuticals in Boston is seeking a Director of Kidney forecasting to build and evolve forecasting capabilities across assets and disease areas. You will lead model development, refine logic, and ensure analyses inform strategy.

As a senior partner to Marketing, Finance, Market Access, Medical and other stakeholders, you will translate data into actionable insights, drive scenario planning, and support portfolio decisions with speed and rigor.