Head of Clinical Operations & Portfolio Delivery

Lindus; United States; Remote; USD 260,000 - 380,000; Full time

Benefits offered by this job

Competitive salary

Stock options

27 days annual leave

Health insurance

Wellness allowance

Parental leave

Learning & development allowance

Company events

Gym/retail discounts

Lunch voucher

Charity partnership

Job summary

Lindus Health seeks a Senior Director of Clinical Operations to own the delivery of one asset from start-up to close-out. You will oversee clinical and regulatory execution, ensure quality, and drive on-time, on-budget delivery while guiding SOPs and trial systems across the portfolio.

You will mentor teams, shape safety and clinical judgment, and collaborate with CMOs, ClinOps, Quality, and Product to raise the overall portfolio standards.

Qualifications

• 15+ years in clinical operations with hands-on delivery across multiple Phase 2 trials.
• Experience with complex neurology trials in chronic indications, ideally Parkinson’s disease.
• Real, first-hand experience making clinical, quality and safety judgement calls in real time across trials.
• Track record of senior review and sign-off on essential trial documents (monitoring plans, RAMPs, protocol deviations, eTMF readiness).
• Proportionate, risk-based approach to clinical oversight focusing on material risks.
• Track record of contributing to or leading SOP and process design at portfolio or function level.
• Broad experience across trial types, phases and therapeutic areas with mentorship for junior staff.
• Comfort shaping trial systems (EDC, CTMS, eTMF) rather than just using them.
• Portfolio-wide authority role and hands-on trial leadership when ramped in.
• Experience across regulatory jurisdictions; FDA preferred.

Responsibilities

• Lead clinical operations on an asset from start-up to close-out.
• Serve as SME for Clinical Ops across the portfolio to ensure quality and compliance.
• Sign-off on essential trial documentation and quality issues; collaborate with cross-functional leads to resolve issues.

Skills

Years of experience

Neurology trials

Clinical judgment

SOP/process design

Risk-based oversight

Stakeholder leadership

Trial systems knowledge

Portfolio governance

Regulatory affairs

Tools

EDC

CTMS

eTMF

Job description

Lindus Health seeks a Senior Director of Clinical Operations to own the delivery of one asset from start-up to close-out. You will oversee clinical and regulatory execution, ensure quality, and drive on-time, on-budget delivery while guiding SOPs and trial systems across the portfolio.

You will mentor teams, shape safety and clinical judgment, and collaborate with CMOs, ClinOps, Quality, and Product to raise the overall portfolio standards.