Head of Clinical AI Research & Trial Design

AstraZeneca; Cambridge (MA); Hybrid; USD 203,000 - 305,000; Full time

Benefits offered by this job

401(k) plan

Paid vacation

Health benefits

Equity-based long-term incentive

Job summary

AstraZeneca is building a world-class AI capability for Clinical Development within the Enterprise AI Unit, aiming to redesign how AI supports medicines from design to delivery. We are hiring a Head of Clinical AI Research to set and lead the AI research agenda and to guide a team of researchers working at the frontier of AI in clinical development.

You will define the scientific portfolio, establish standards, translate cutting-edge research into regulated, real-world methods, and mentor a

Qualifications

• PhD in ML, CS, or biomedical informatics with strong publication record.
• Proven leadership in guiding multiple research workstreams.
• Experience with clinical/biopharma domain is a plus.

Responsibilities

• Set and lead the research agenda for clinical AI methods across Phases I‑III.
• Lead a team of AI/ML researchers on high-value clinical development problems.
• Establish methodological standards and reusable research artifacts.
• Translate research into regulated, real-world methods and collaborate with cross-functional partners.
• Represent AstraZeneca publicly through publications and collaborations.

Skills

PhD in ML/CS/biomed informatics

8+ years AI/ML research

Original publications

Research leadership

Multimodal foundation models

LLMs & NLP

AI evaluation

Education

PhD in machine learning, computer science, biomedical informatics

Job description

AstraZeneca is building a world-class AI capability for Clinical Development within the Enterprise AI Unit, aiming to redesign how AI supports medicines from design to delivery. We are hiring a Head of Clinical AI Research to set and lead the AI research agenda and to guide a team of researchers working at the frontier of AI in clinical development.

You will define the scientific portfolio, establish standards, translate cutting-edge research into regulated, real-world methods, and mentor a