Head of Cell Therapy Materials & Traceability

AstraZeneca plc; Los Angeles (CA); On-site; USD 124,000 - 186,000; Full time

Job summary

AstraZeneca Cell Therapy is seeking an Associate Director, Materials Management to lead patient materials management across autologous and allogeneic cell therapy programs. You will own COI/COC traceability from receipt to drug product pack-out, coordinating with manufacturing, quality and logistics teams while maintaining GMP-compliant processes.

The role emphasizes on-site leadership at Santa Monica and Tarzana facilities, with focus on implementing digital systems, real-time milestone

Qualifications

• Bachelor’s degree in Supply Chain, Engineering, Life Sciences, or a related field.
• 8+ years in biopharma supply chain, logistics or cell therapy operations.
• Strong understanding of COI/COC controls and the operational requirements for patient material receipt and product pack-out.
• Experience in real-time issue resolution, exception management, shipment recovery, temperature excursion response, escalation handling, investigations and CAPA leadership.
• Working knowledge of GDP, GMP, and GxP requirements, including deviation and quality processes.
• Ability to lead through influence and maintain high execution quality in a fast-paced environment.
• Strong written and verbal communication skills.

Responsibilities

• Lead patient materials management across autologous and allogeneic programs, ensuring COI/COC traceability from apheresis through drug product pack-out.
• Coordinate apheresis receipt and drug product pack-out schedule with manufacturing, quality, and logistics teams.
• Own COI and COC processes at the site including SOPs/work instructions and monitor status with digital tools.
• Ensure execution discipline for COI/COC traceability and adherence to workflows, documentation, and SOPs.
• Support readiness for new studies, products, and country expansions, including onboarding activities and mock shipments.
• Lead exception management and escalation when traceability deviations occur, coordinating recovery actions.
• Support investigations, root-cause assessments, and CAPA activities.
• Track operational metrics and identify opportunities to improve reliability and consistency.

Skills

COI/COC controls

GDP/GMP/GxP knowledge

Real-time issue resolution

Exception management

Communication skills

Education

Bachelor’s degree in Supply Chain, Engineering, Life Sciences

Advanced degree such as MS or MBA

Tools

Power BI

Smartsheet

Excel

Job description

AstraZeneca Cell Therapy is seeking an Associate Director, Materials Management to lead patient materials management across autologous and allogeneic cell therapy programs. You will own COI/COC traceability from receipt to drug product pack-out, coordinating with manufacturing, quality and logistics teams while maintaining GMP-compliant processes.

The role emphasizes on-site leadership at Santa Monica and Tarzana facilities, with focus on implementing digital systems, real-time milestone